DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment loqs and stau2

DIOPT Version :9

Sequence 1:	NP_609646.1	Gene:	loqs / 34751	FlyBaseID:	FBgn0032515	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_021325790.1	Gene:	stau2 / 393899	ZFINID:	ZDB-GENE-040426-687	Length:	684	Species:	Danio rerio

Alignment Length:	388	Identity:	97/388 - (25%)
Similarity:	158/388 - (40%)	Gaps:	82/388 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 ETDANGLAMKTPVSILQELLSRRGITPGYELVQIEGAIHEPTFRFRVSFKDKDTPFTAMGAGRSK 189
            ||:.|..|.|:.:|::.|:..:|.:...:|:::..|..|..:|..||:..:    |:|.|.|.||
Zfish   269 ETEENSDASKSEISLVYEIALKRNLPVNFEVLKESGPPHMKSFLTRVTVGE----FSAEGEGNSK 329

  Fly   190 KEAKHAAARALIDKLIGAQLPESPSSSAGPSV-------TGLTVAGSGGDGNANATGGGDASDKT 247
            |.:|..||.:::.:|  .:||..|.... |.|       |.|......|.|.
Zfish   330 KLSKKRAALSILQEL--KKLPVLPVVEK-PKVHYKKRPKTILKTGPEYGQGM------------- 378

  Fly   248 VGNPIGWLQEMCMQRRWPPPSYETETEVGLPHERLFTIACSILNYREMGKGKSKKIAKRLAAHRM 312
              |||..|.::...::...|.|...:|.|:|..|.|.:...:......|.|.:||:|||.||..|
Zfish   379 --NPISRLAQIQQAKKEKEPEYMLLSERGMPRRREFIMQVKVGTEVTTGTGPNKKVAKRNAAEAM 441

  Fly   313 WMR--------LQETP--ID----SGK-----------------ISDSICGELE-----GEPRSS 341
            .::        ||.||  :|    :|:                 :|..:..|:|     |.|.:.
Zfish   442 LLQLGYKASTPLQNTPEKMDNKGWNGQRAAFPETTSNTQKGILHLSPDVYQEMEASRNKGVPGAP 506

  Fly   342 ENYYGELKDI----SVPTLTTQHSNKVSQFHKTLKNATGKK----LLKLQKTCLKNNKIDYIKLL 398
            .| :...|:|    :.|..|....|..:...:.|.:.|...    :||.:...|....|...:.|
Zfish   507 GN-FPTAKEIGQGSAGPFCTPSVGNTATIAKELLLSGTSPTAEALVLKGKAPALACGSIQPSQQL 570

  Fly   399 GEIATENQFEVTYVDIE-EKTFSGQFQCLVQLSTLPVGVC-HGSGPTAADAQRHAAQNALEYL 459
            ..:|....|:|.|.|.: :|.|      :..|:..||.:. ||.|.:...:...||.:||:.|
Zfish   571 EYLAHIQGFQVQYSDRQTDKEF------MTYLTLSPVQMTFHGIGSSIPASHDQAALSALKQL 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM	136..204	CDD:214634	19/67 (28%)
		DSRM	250..316	CDD:238007	21/73 (29%)
		DSRM	394..460	CDD:214634	19/68 (28%)
stau2	XP_021325790.1	DSRM	81..142	CDD:214634
		DSRM	168..252	CDD:214634
		DSRM	281..345	CDD:214634	20/69 (29%)
		DSRM	380..446	CDD:214634	20/65 (31%)
		Staufen_C	526..631	CDD:318642	26/108 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740