Protein Alignment loqs and ILF3

DIOPT Version :10

• Sequence 1: NP_609646.1
• Gene: loqs / 34751
• FlyBaseID: FBgn0032515
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_060090.2
• Gene: ILF3 / 3609
• HGNCID: 6038
• Length: 898
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 62/224 - (27%)
• Similarity: 89/224 - (39%)
• Gaps: 52/224 - (23%)

  Fly   136 PVSILQELLSRRGITPG--YELVQIEGAIHEPTFRFRV-----SFKDKDTPFTAMGAGRSKKEAK 193
            |...:..|:....:.||  |:||...|.:|.|.|...|     ||:         .:|.|||.||
Human   399 PPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFE---------ASGPSKKTAK 454

  Fly   194 -HAAARALIDKLIGAQLP---ESPSSSAG-----------------PSVTGLTVAGSGGDGNA-- 235
             |.|.:.|.|  :|  ||   |...||.|                 |.|..::...:....:|
Human   455 LHVAVKVLQD--MG--LPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATA 515

  Fly   236 -NATGGGDASDKTVGNPIGWLQEMCMQRRWPPPSYETETEVGLPHERLFTIACSILNYREMGKGK 299
             |....|....|...||:..|.|   :||  ...||..:|.|..|::.|.:...:...:..|.|.
Human   516 ENVKQQGPILTKHGKNPVMELNE---KRR--GLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS 575

  Fly   300 SKKIAKRLAAHRMWMRL-QETP--IDSGK 325
            :||:||..||.....:| .:||  :|:.|
Human   576 NKKVAKAYAALAALEKLFPDTPLALDANK 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM_PRKRA-like_rpt1	134..206	CDD:380691	24/77 (31%)
		DSRM_PRKRA-like_rpt2	250..316	CDD:380692	20/65 (31%)
		DSRM_PRKRA-like_rpt3	393..463	CDD:380693
ILF3	NP_060090.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..86
		DZF	88..342	CDD:128842
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	363..401		1/1 (100%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	371..389
		DSRM_ILF3_rpt1	399..470	CDD:380739	27/83 (33%)
		DSRM_ILF3_rpt2	524..595	CDD:380741	22/75 (29%)
		Interaction with PRMT1. /evidence=ECO:0000269|PubMed:10749851	613..898
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	629..664
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..898