DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loqs and Prkra

DIOPT Version :9

Sequence 1:	NP_609646.1	Gene:	loqs / 34751	FlyBaseID:	FBgn0032515	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001019951.1	Gene:	Prkra / 311130	RGDID:	1306707	Length:	313	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	118/339 - (34%)
Similarity:	160/339 - (47%)	Gaps:	66/339 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 KTPVSILQELLSRRGITPGYELVQIEGAIHEPTFRFRVSFKDKDTPFTAMGAGRSKKEAKHAAAR 198
            |||:.:|.|..::....|.||..:.:..:|.|||.|||:..|    .|..|.|.|||.|||.||.
  Rat    33 KTPIQVLHEYGTKTKNIPVYECERSDVQVHVPTFTFRVTVGD----ITCTGEGTSKKLAKHRAAE 93

  Fly   199 ALIDKL-IGAQL------PESPSSSAGPSVTGLTVAGSGGDGNANATGGGDASDKTVGNPIGWLQ 256
            |.|:.| ..|.:      |..|..|..|                          |...||||.||
  Rat    94 AAINILKANASICFAVPDPLMPDPSKQP--------------------------KNQLNPIGSLQ 132

  Fly   257 EMCMQRRWPPPSYETETEVGLPHERLFTIACSILNYREMGKGKSKKIAKRLAAHRMWMRLQETPI 321
            |:.:...|..|.|....|.|..|:|.:|..|.:.::.|.|||.|||.|||.||.:...:....
  Rat   133 ELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNI-- 195

  Fly   322 DSGKISDSICGELEGEPRSSENYYGELKDISVPTLTTQHSNKVSQFHKTLKNATGKKLLKLQKTC 386
                              |.||:......:......|.||         |:|:.|:|:..|:::.
  Rat   196 ------------------SPENHISLTNVVGHSLGCTWHS---------LRNSPGEKINLLKRSL 233

  Fly   387 LKNNKIDYIKLLGEIATENQFEVTYVDIEEKTFSGQFQCLVQLSTLPVGVCHGSGPTAADAQRHA 451
            |.....|||:||.|||.|..|.:||:||||.:.:||:|||.:|||.|:.||||||.:..:||..|
  Rat   234 LSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDA 298

  Fly   452 AQNALEYLKIMTKK 465
            |.|||:||||:.::
  Rat   299 AHNALQYLKIIAER 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM	136..204	CDD:214634	27/67 (40%)
		DSRM	250..316	CDD:238007	28/65 (43%)
		DSRM	394..460	CDD:214634	38/65 (58%)
Prkra	NP_001019951.1	Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	1..103		30/73 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		DSRM	35..100	CDD:214634	27/68 (40%)
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	102..195		34/118 (29%)
		DSRM	126..192	CDD:238007	28/65 (43%)
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	195..313		54/147 (37%)
		DSRM	241..307	CDD:214634	38/65 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352101
Domainoid	1	1.000	81	1.000	Domainoid score	I8339
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2738
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4053
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1093169at2759
OrthoFinder	1	1.000	-	-		FOG0003036
OrthoInspector	1	1.000	-	-		otm46293
orthoMCL	1	0.900	-	-		OOG6_107751
Panther	1	1.100	-	-	LDO	PTHR46205
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2027
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760