DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loqs and Zfr2

DIOPT Version :9

Sequence 1:	NP_609646.1	Gene:	loqs / 34751	FlyBaseID:	FBgn0032515	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001030067.2	Gene:	Zfr2 / 103406	MGIID:	2143792	Length:	874	Species:	Mus musculus

Alignment Length:	368	Identity:	78/368 - (21%)
Similarity:	116/368 - (31%)	Gaps:	126/368 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QASPNPVQTGFAPRRHYNNLVGLGNGNAVSGSPVKGAPL-GQRHVKLKKEKISAQVAQLSQPGQL 87
            :|.|.|      |..||..:..:    :.:|.......| ||:|    ::|.:||... :||.
Mouse   196 KAGPRP------PSMHYCEVCRV----SCAGPQTYRDHLEGQKH----RKKQAAQRTS-TQPS-- 243

  Fly    88 QLSDVGDPALAGGSGLQGGVGLMGVILPSDEALKFVSETDANGLAMKTPVSILQELLSRRGITPG 152
                 |.|  .|...|..|             |..||.|.|:..|
Mouse   244 -----GGP--RGSQSLHCG-------------LCAVSCTGADAYA-------------------- 268

  Fly   153 YELVQIEGAIHEPTFRFRV----SFKDKDTP----FTAMGAGRSKKEAKHAAARALIDKLIGAQL 209
               ..:.||.|:..|:...    ....:.||    :|.......:...||.|.........|...
Mouse   269 ---AHMRGARHQKVFKLHTRLGKPIPSEPTPRSVTYTRGSDSTPETSVKHEAHARHSSHTQGRPA 330

  Fly   210 PE--SPSSSAGPSVTGLTVAGSGGDG-------NANATGGGDASDKTVGN--PIG--WLQEMCMQ 261
            |.  |.:|..||... .|:.|..||.       .|...|.|:||..: |:  |:|  :::|:|
Mouse   331 PAKGSAASRKGPPEL-QTMHGRPGDRRPSHFKVEATRGGPGEASGSS-GDMAPVGTEYVEEVC-- 391

  Fly   262 RRWPPPSYETETEVGLPHERLFTIACSI----------------LNYRE----------MGKGKS 300
                      ..|..:...|.....||.                |.||:          ...|..
Mouse   392 ----------SDEGKVIRFRCKLCECSFNDRNARDMHLTGRRHRLQYRKKVDPTLPVAARPSGPI 446

  Fly   301 KKI-AKRLAAHRMWMRLQETPIDSGKISDSICGELEGEPRSSE 342
            ::: ||||..|  |.::| |.::..:..||...:.|...|..|
Mouse   447 QRVLAKRLQRH--WQQVQ-TQLEDTRRWDSELRQQEEHSRQPE 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM	136..204	CDD:214634	10/75 (13%)
		DSRM	250..316	CDD:238007	18/96 (19%)
		DSRM	394..460	CDD:214634
Zfr2	NP_001030067.2	CytochromB561_N	<72..>169	CDD:286826
		ZnF_U1	205..232	CDD:197732	7/34 (21%)
		C2H2 Zn finger	207..253	CDD:275371	13/63 (21%)
		ZnF_U1	252..283	CDD:197732	12/66 (18%)
		C2H2 Zn finger	254..276	CDD:275371	9/57 (16%)
		ZnF_U1	399..430	CDD:197732	5/30 (17%)
		C2H2 Zn finger	402..424	CDD:275371	2/21 (10%)
		DZF	586..837	CDD:295427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930