Protein Alignment CG9302 and EUG1

DIOPT Version :10

• Sequence 1: NP_609645.2
• Gene: CG9302 / 34750
• FlyBaseID: FBgn0032514
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_010806.1
• Gene: EUG1 / 852130
• SGDID: S000002926
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 520
• Identity: 95/520 - (18%)
• Similarity: 165/520 - (31%)
• Gaps: 203/520 - (39%)

  Fly   120 VSSMITFMRDPSGDLPWEEDPA----GKDVLHFSDAASFTKHLRKDIRP---MLVMFYVPWCGFC 177
            :|::::|....|..|  .|:.|    |.|:|..::     |..:..|..   :||.|:.|||...
Yeast     8 ISAIVSFCLFASFTL--AENSARATPGSDLLVLTE-----KKFKSFIESHPLVLVEFFAPWCLHS 65

  Fly   178 KKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRF---TYEGE 239
            :.::|...:|::.||.   :.:..:.::.:.|:.:.....|..:|||..|:||:: |   .|.|.
Yeast    66 QILRPHLEEAASILKE---HNVPVVQIDCEANSMVCLQQTINTYPTLKIFKNGRI-FDGQVYRGV 126

  Fly   240 NNKEALVSFMLNPNAKPTPKPKEPEWSADTNSEIVHLTSQG-FEPALKDEKSALVMFYAPWCGHC 303
            ...:.:..:|:..                ..:.:::|.|:. .:|.|::....:|:
Yeast   127 KITDEITQYMIQL----------------YEASVIYLNSEDEIQPYLENATLPVVI--------- 166

  Fly   304 KR----MKPEYEKAALEMKQKKIPGLLAALDATK------------------------------- 333
            .|    :...|::.||::.:..:  .|:.||:..
Yeast   167 NRGLTGLNETYQEVALDLAEDYV--FLSLLDSEDKSLSIHLPNTTEPILFDGNVDSLVGNSVALT 229

  Fly   334 --------------EPSIAEKYKVKGYPTVKFFSNGVFKFE------------------------ 360
                          ||.:..||.....|...||.....:.|
Yeast   230 QWLKVVILPYFTDIEPDLFPKYISSNLPLAYFFYTSEEELEDYTDLFTQLGKENRGQINFIALNS 294

  Fly   361 ---------VNVRE------------------------------------ASKIVEFMRDPKEPP 380
                     :|:||                                    ...||:.::|.:| .
Yeast   295 TMFPHHVRFLNMREQFPLFAIHNMINNLKYGLPQLPEEEYAKLEKPQPLDRDMIVQLVKDYRE-G 358

  Fly   381 PPPPPEKSWEEEEDSKEVLFL-----------DDDNFSSTLKRKKHALVMFYAPWCGHCKHTKPE 434
            ...|..||.|..::.|..::.           |||         |..||.:||.||.|.|...|.
Yeast   359 TAKPIVKSEEIPKEQKSNVYKIVGKTHDDIVHDDD---------KDVLVKYYATWCIHSKRFAPI 414

  Fly   435 FTAAATALQDD----PRIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTKLDYNGGRTSKDFI 495
            :...|..|..|    .:|....:|......|  .:.|.|||||..         |..|..||..|
Yeast   415 YEEIANVLASDESVRDKILIAEVDSGANDIL--SFPVTGYPTIAL---------YPAGNNSKPII 468

  Fly   496  495
            Yeast   469  468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365	2/10 (20%)
		PDI_a_PDIR	144..249	CDD:239295	25/110 (23%)
		PDI_a_PDIR	272..373	CDD:239295	25/219 (11%)
		PDI_a_PDIR	397..498	CDD:239295	30/114 (26%)
EUG1	NP_010806.1	ER_PDI_fam	33..487	CDD:273457	88/493 (18%)