DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9302 and Tmx1

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_082615.1	Gene:	Tmx1 / 72736	MGIID:	1919986	Length:	278	Species:	Mus musculus

Alignment Length:	223	Identity:	43/223 - (19%)
Similarity:	80/223 - (35%)	Gaps:	73/223 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 LTSQGFEPALKDEKSALVMFYAPWCGHCKRMKPEYEKAA-----LEMKQKKIPGLLAALDATKEP 335
            ||.:.:...|:.|  .::.||||||..|:.::||:|..|     ||:|       :|.:|.|::.
Mouse    34 LTDENWTSLLEGE--WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVK-------VAKVDVTEQT 89

  Fly   336 SIAEKYKVKGYPTVKFFSNGVFKFEVNVREASKIVEFMRDPKEPPPPPPPEKSWEEEED------ 394
            .::.::.:...|::....:|.|:..|..|.....:.|:.|           |.|:..|.
Mouse    90 GLSGRFIITALPSIYHCKDGEFRRYVGPRTKKDFINFVSD-----------KEWKNIEPISSWFG 143

  Fly   395 --------------------SKEVLFLDDDN-----------FSSTLKRKKHALVMFYAPWC--- 425
                                :....|:.|..           |::.|......|.|.:...|
Mouse   144 PSSVLMTMMSALFQLSVYIRTSHSYFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCP 208

  Fly   426 --------GHCKHTKPEFTAAATALQDD 445
                    .:.|.|.|||:.....::::
Mouse   209 SKRRKPQQQYAKKTSPEFSQPLKKVEEE 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295
		ER_PDI_fam	166..500	CDD:273457	43/223 (19%)
		PDI_a_PDIR	272..373	CDD:239295	26/101 (26%)
		PDI_a_PDIR	397..498	CDD:239295	12/71 (17%)
Tmx1	NP_082615.1	PDI_a_TMX	30..129	CDD:239292	27/103 (26%)
Tmx1	NP_082615.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	217..278		5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910