DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and tmx3a

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001018393.2	Gene:	tmx3a / 553578	ZFINID:	ZDB-GENE-050522-396	Length:	437	Species:	Danio rerio

Alignment Length:	206	Identity:	53/206 - (25%)
Similarity:	86/206 - (41%)	Gaps:	34/206 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 FTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNI 218
            ||:..:.::  .||.||.|||.:|...:|.:.:...|||:.|..:... .::...:..|...|||
Zfish    30 FTEFRQNEL--WLVEFYAPWCAYCHTFEPVWTEVGAELKSLGSPVNVG-KIDTTAHTSIATEFNI 91

  Fly   219 TGFPTLIYFENGKLRFTYEGENNKEALVSFMLNPNAKPTPKPKEPEWSADTNSEIVHLTS-QGFE 282
            .|:||:..|: |.|.|.|:|...|:.::.| .|..:.|..:|               |:| |.|:
Zfish    92 RGYPTIKLFK-GDLSFDYKGPRTKDGIIEF-TNRVSGPVVRP---------------LSSVQLFQ 139

  Fly   283 PALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEK-YKVKGY 346
            ..:.......|     :.|....:|.||.|||.|.       ::.....|....|..| ..::..
Zfish   140 HVMSRHDVIFV-----YIGGESLLKKEYYKAATEF-------IVHTYFFTASEEILPKAVTLQDV 192

  Fly   347 PTVKFFSNGVF 357
            |.|..|.:|.:
Zfish   193 PAVAVFKDGTY 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295	29/94 (31%)
		ER_PDI_fam	166..500	CDD:273457	51/194 (26%)
		PDI_a_PDIR	272..373	CDD:239295	20/88 (23%)
		PDI_a_PDIR	397..498	CDD:239295
tmx3a	NP_001018393.2	PDI_a_TMX3	22..125	CDD:239298	31/99 (31%)
tmx3a	NP_001018393.2	Thioredoxin_6	155..332	CDD:290560	14/56 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910