DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and txndc5

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_005162560.1	Gene:	txndc5 / 406289	ZFINID:	ZDB-GENE-040426-1951	Length:	403	Species:	Danio rerio

Alignment Length:	402	Identity:	122/402 - (30%)
Similarity:	183/402 - (45%)	Gaps:	77/402 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 SGDLPWEEDPAGK---DVLHFSDAASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKAS---T 189
            |.|...|||...|   .|..|:||.|...|        .|||:.||||.|::::..:.:.:   .
Zfish    19 SCDNDTEEDEHAKHTYTVEMFNDAISTAPH--------FVMFFAPWCGHCQRLQGTWNELADKYN 75

  Fly   190 ELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRFTYEGENNKEALVSFML---- 250
            .::....|::.....:..:...|.  ..|.|:|||..|:..:....|:|..:.:||.::||
Zfish    76 SMEAPPAYVVKVDCTKDTKFCSIE--HGIRGYPTLKLFKPEQEAVKYQGPRDLQALENWMLKTLQ 138

  Fly   251 ----NPNAKPTPKPKEPEWSADTNSEIVHLTSQGFEPALKDEKSALVMFYAPWCGHCKRMKPEYE 311
                .|.::|.| ||.||    ....:..||:..|:..:. :.|..|.|:||||||||.|.|.:|
Zfish   139 EEPEEPQSEPEP-PKVPE----PKQGLYELTATNFKSHIA-KGSHFVKFFAPWCGHCKAMAPTWE 197

  Fly   312 KAALEMKQK---KIPGLLAALDATKEPSIAEKYKVKGYPTVKFFSNG-----------VFKFEVN 362
            :.|...:..   ||    :.:|.|:...:....:|:||||:.||::|           :..|:..
Zfish   198 QLASSFEHSDSIKI----SKVDCTQHYEVCSDNQVRGYPTLLFFTDGEKIDQYKGKRDLDSFKEF 258

  Fly   363 VREASKIVEFMRDPK-------EPPPPPPPEKSWEEEEDSKEVLFLDDDNFSSTLKRKKHALVMF 420
            |....|..|...:|:       |.||...|||      ....||.|.:.||..|: .|..:.:.|
Zfish   259 VDNHVKAAESKDEPEKEEEHTHEIPPSAEPEK------QESNVLVLTESNFDETV-AKGLSFIKF 316

  Fly   421 YAPWCGHCKHTKP--------EFTAAATALQDDPRIAFVAIDCTKLAALCAKYNVRGYPTILYFS 477
            |||||||||:..|        ||....     |.:||  .:|||....||.:::||||||:|.|.
Zfish   317 YAPWCGHCKNLAPTWDDLSQKEFPGLT-----DVKIA--KVDCTVERTLCNRFSVRGYPTLLMFR 374

  Fly   478 YLKTKLDYNGGR 489
            ..:...::||||
Zfish   375 AGQQGEEHNGGR 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365	122/402 (30%)
		PDI_a_PDIR	144..249	CDD:239295	26/107 (24%)
		ER_PDI_fam	166..500	CDD:273457	110/364 (30%)
		PDI_a_PDIR	272..373	CDD:239295	34/114 (30%)
		PDI_a_PDIR	397..498	CDD:239295	40/101 (40%)
txndc5	XP_005162560.1	ER_PDI_fam	33..403	CDD:273457	116/388 (30%)
		Thioredoxin_like	34..133	CDD:294274	26/108 (24%)
		PDI_a_ERp46	159..259	CDD:239303	31/104 (30%)
		PDI_a_ERp46	294..395	CDD:239303	40/101 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522268at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820