DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and CG18130

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_572772.1	Gene:	CG18130 / 32161	FlyBaseID:	FBgn0030359	Length:	706	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	83/429 - (19%)
Similarity:	131/429 - (30%)	Gaps:	165/429 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AKSKTSAVQDDIAEYKDFKKLLRTKNNVLALYVTSAKSAAAELKIFREAAE-----------AIR 71
            :|:||.::..:.|..                    |:..||:|....||:|           |:.
  Fly   325 SKAKTKSISHEEAHL--------------------AEEEAADLDAEEEASEEETVMPEPGGDAMG 369

  Fly    72 GTGTMLLLDCGQQDRKKLCKKLKVSP------DPYAIKHYKDGDFHKDYDRQLSVSS-------- 122
            |..:|...:            |::.|      |...::..|:.:..|...|..:|..
  Fly   370 GLPSMPGFE------------LEIEPVDEAGEDEEEVQEIKEEEPSKPLTRTKTVKMPPIWVPNS 422

  Fly   123 --------MITFMRDPSGDLPWEEDPAGKDVLHFSDAASFTKHLRKDIRPMLVMFY--VPWCGFC 177
                    .:.|....||.||.:..|....|:...||:.     ||:|..::....  ||..||.
  Fly   423 RRTHAALIYVFFRGQTSGFLPPDPKPEPPHVIMAFDASK-----RKEIMHVIDRHKDDVPLYGFF 482

  Fly   178 KKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRFTYEGENNK 242
            ...:|:..:            |.|.:.::.|::|......|.            |:......|..
  Fly   483 SSAEPDEAE------------LIATSTDKYESSPHSSGDKIV------------LKVNKVQSNMM 523

  Fly   243 EALVSF---MLNPNA--------KPTPKPKEPEWSADTNSEIVHLTSQGFEPALKDEKSALVMFY 296
            .:|||:   .::||.        |..|:..:|:      .|:|      .|...|.:||
  Fly   524 LSLVSYGPSYVSPNVTVGKDEALKFFPEDYKPQ------EEVV------VEVEKKKKKS------ 570

  Fly   297 APWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEKYKVKGYPTVKFFSNGVFKFEV 361
                           |.|.|:.|:......||..|...||.|.               ...:.|.
  Fly   571 ---------------KRATEINQEMEAAAAAAAAAAAHPSEAP---------------APVEAEA 605

  Fly   362 NVREASKIVEFMRDP--KEPPP--------PPPPEKSWE 390
            :..||...||....|  .|.||        |||.|.:.|
  Fly   606 HAAEAPAAVEGDAAPAAAEAPPAGDAAPVAPPPAEPAAE 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365	19/139 (14%)
		PDI_a_PDIR	144..249	CDD:239295	21/109 (19%)
		ER_PDI_fam	166..500	CDD:273457	50/248 (20%)
		PDI_a_PDIR	272..373	CDD:239295	21/100 (21%)
		PDI_a_PDIR	397..498	CDD:239295
CG18130	NP_572772.1	TRX_NDPK	11..112	CDD:239246
CG18130	NP_572772.1	DUF4746	234..556	CDD:292550	52/291 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910