DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and prtp

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001188583.1	Gene:	prtp / 32124	FlyBaseID:	FBgn0030329	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	101/393 - (25%)
Similarity:	182/393 - (46%)	Gaps:	43/393 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 EEDPAGKDVLHFS---DAASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYI 198
            :|:..||....|:   |..:|...:...  .:.|.|:.||||.||:::|.:.:.:..:......:
  Fly    27 QEEDTGKQDKQFTVELDPETFDTAIAGG--NVFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKV 89

  Fly   199 LAAMNVERQENAPIRKMFNITGFPTLIYFENGKLR-FTYEGENNKEALVSFM---LNPNAKPTPK 259
            :.| .|:..::..:.....:||:|||..|:.|:.. ..::|..:..|:..|:   |:..|:....
  Fly    90 IIA-KVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDFINKELSAPAEADLG 153

  Fly   260 PKEPEWSADTN-SEIVHLTSQGFEPALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEM-KQKKI 322
            ..:.|...:.| .::|.||...|...: ...:..|.|:||||.||:|:.|.:|..|.|: |:..:
  Fly   154 EVKREQVENLNIGKVVDLTEDTFAKHV-STGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTV 217

  Fly   323 PGLLAALDATKEPSIAEKYKVKGYPTVKFFSNG--VFKFEVNVREASKIVEFMRDPKEPPPPPPP 385
              .::.:|.|:..||.:.::||||||:.:..:|  :.|:. ..|:.|.:..::    |.....|.
  Fly   218 --TISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYS-GARDLSTLKTYV----EKMVGVPL 275

  Fly   386 EKSWEEEEDSKEVL-----------------FLDDDNFSSTLKRKKHALVMFYAPWCGHCKHTKP 433
            ||:..|..|.|.|:                 ...:|.|...: .:..|.:.|||||||||:..:|
  Fly   276 EKTAGEAGDEKVVIEEVAGEEDAAKKLTPQQLTGEDEFDQAI-AEGVAFIKFYAPWCGHCQKLQP 339

  Fly   434 EFTAAATAL-QDDPRIAFVAIDCT--KLAALCAKYNVRGYPTILYFSYLKTKLDYNGGRTSKDFI 495
            .:...||.. |....:....:|||  :...:|....|.||||:..:...:.:.:|.|.|:..:..
  Fly   340 TWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYPTLFLYKNGQRQNEYEGSRSLPELQ 404

  Fly   496 AYM 498
            ||:
  Fly   405 AYL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295	23/108 (21%)
		ER_PDI_fam	166..500	CDD:273457	95/361 (26%)
		PDI_a_PDIR	272..373	CDD:239295	32/103 (31%)
		PDI_a_PDIR	397..498	CDD:239295	30/120 (25%)
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	23/104 (22%)
		ER_PDI_fam	39..409	CDD:273457	97/381 (25%)
		PDI_a_ERp46	167..267	CDD:239303	32/103 (31%)
		PDI_a_ERp46	303..407	CDD:239303	29/104 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522268at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45672
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850