DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and Pdia6

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001004442.1	Gene:	Pdia6 / 286906	RGDID:	628688	Length:	445	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	83/264 - (31%)
Similarity:	136/264 - (51%)	Gaps:	42/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 TNSEIVHLTSQGF-EPALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDAT 332
            ::.:::.||...| ...::.:...||.|||||||||:|:.||::|||..:|.....|   |::|.
  Rat    28 SSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKVG---AVNAD 89

  Fly   333 KEPSIAEKYKVKGYPTVKFFS---------NGVFKFEVNVREA-SKIVEFMRD-----------P 376
            |..|:..:|.|:|:||:|.|.         .|....|..|..| |.:.:.::|           .
  Rat    90 KHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG 154

  Fly   377 KEPPPPPPPEKSWEEEEDSKEVLFLDDDNF-SSTLKRKKHALVMFYAPWCGHCKHTKPEFTAAAT 440
            |:         ...:....|:|:.|.||.| .:.|..:...:|.||||||||||:.:||:.||||
  Rat   155 KQ---------GRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAT 210

  Fly   441 ALQDDP--RIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTKLDYNGGRTSKDFIA-----YM 498
            .:::..  ::...|:|.|....|.::|.::|:|||..|...::.:||:||||..|.::     :.
  Rat   211 EVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFS 275

  Fly   499 NNPP 502
            :|.|
  Rat   276 DNAP 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295
		ER_PDI_fam	166..500	CDD:273457	81/260 (31%)
		PDI_a_PDIR	272..373	CDD:239295	38/111 (34%)
		PDI_a_PDIR	397..498	CDD:239295	40/108 (37%)
Pdia6	NP_001004442.1	PDI_a_P5	31..133	CDD:239299	36/104 (35%)
		PDI_a_P5	166..271	CDD:239299	40/104 (38%)
		P5_C	280..409	CDD:239281	83/264 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810