Protein Alignment CG9302 and P4hb

DIOPT Version :10

• Sequence 1: NP_609645.2
• Gene: CG9302 / 34750
• FlyBaseID: FBgn0032514
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_035162.1
• Gene: P4hb / 18453
• MGIID: 97464
• Length: 509
• Species: Mus musculus
• Alignment Length: 487
• Identity: 111/487 - (22%)
• Similarity: 165/487 - (33%)
• Gaps: 159/487 - (32%)

  Fly   137 EEDPAGKDVL-----HFSDAASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGG 196
            |||    :||     :|.:|.:..|:|       ||.||.||||.||.:.|||.||:.:||.:|.
Mouse    24 EED----NVLVLKKSNFEEALAAHKYL-------LVEFYAPWCGHCKALAPEYAKAAAKLKAEGS 77

  Fly   197 YILAAMNVERQENAPIRKMFNITGFPTLIYFENGKL----------------------------- 232
            .|..| .|:..|.:.:.:.:.:.|:||:.:|:||..
Mouse    78 EIRLA-KVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATT 141

  Fly   233 ----------------------------------------------------------------- 232
                                                                             
Mouse   142 LSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSKYQLDKDGVV 206

  Fly   233 --------RFTYEGENNKEALVSFMLNPNAKPTPKPKEPEWSADTNSEIVHLTSQGFEPALKDEK 289
                    |..:|||..||.|:.| :..|..|.               ::..|.|........|.
Mouse   207 LFKKFDEGRNNFEGEITKEKLLDF-IKHNQLPL---------------VIEFTEQTAPKIFGGEI 255

  Fly   290 SALVMFYAPWCGHCKRMKPEYE------KAALEMKQKKIPGLLAALDATKEPSIAEKY--KVKGY 346
            ...::.:.|      :...:|:      |.|.|..:.||..:....|.|....|.|.:  |.:..
Mouse   256 KTHILLFLP------KSVSDYDGKLSSFKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEEC 314

  Fly   347 PTVKFFS----NGVFKFEVNVREASKIVEFM-RDPKEPPPPPPPEKSWEEEEDSKEVLFLDDDNF 406
            |.|:..:    ...:|.|.:...|.||.||. |..:....|....:...|:.|.:.|..|...||
Mouse   315 PAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANF 379

  Fly   407 SS-TLKRKKHALVMFYAPWCGHCKHTKPEFTAAATALQDDPRIAFVAIDCTKLAALCAKYNVRGY 470
            .. ....||:..|.||||||||||...|.:.......:|...|....:|.|.......|  |..:
Mouse   380 EEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVK--VHSF 442

  Fly   471 PTILYF--SYLKTKLDYNGGRTSKDFIAYMNN 500
            ||:.:|  |..:|.:||||.||...|..::.:
Mouse   443 PTLKFFPASADRTVIDYNGERTLDGFKKFLES 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295	41/211 (19%)
		PDI_a_PDIR	272..373	CDD:239295	23/112 (21%)
		PDI_a_PDIR	397..498	CDD:239295	36/103 (35%)
P4hb	NP_035162.1	ER_PDI_fam	26..476	CDD:273457	109/485 (22%)
		Prevents secretion from ER	506..509