DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9302 and pdi-6

DIOPT Version :9

Sequence 1:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_509190.1	Gene:	pdi-6 / 180974	WormBaseID:	WBGene00015168	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	87/250 - (34%)
Similarity:	124/250 - (49%)	Gaps:	31/250 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 EIVHLTSQGFE-PALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGL--LAALDATK 333
            ::|.||...|: ..:..:...:|.||||||||||.:.|||:|||..:|     |:  :.|:|.|:
Worm    25 DVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALK-----GVAKVGAVDMTQ 84

  Fly   334 EPSIAEKYKVKGYPTVKFFS---------NGVFKFEV----NVREASKIVEFMRDPKEPPPPPPP 385
            ..|:...|.|:|:||:|.|.         ||....:.    .:.||.|.|......|........
Worm    85 HQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARLGGKSSGSSSSG 149

  Fly   386 EKSWEEEE----DSKEVLFLDDDNFSS-TLKRKKHALVMFYAPWCGHCKHTKPEFTAAATALQDD 445
            ..|...:.    ...||:.|.|.||.. .|..|...||.|:||||||||..:|::.|||:.|:..
Worm   150 SGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCKSLEPQWKAAASELKGK 214

  Fly   446 PRIAFVAIDCTKLAALCAKYNVRGYPTILYF---SYLKTKLDYNGGRTSKDFIAY 497
            .|:.  |:|.|....:..|:.:||:|||.||   |.:....||:|||.|.|.:|:
Worm   215 VRLG--ALDATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGGRQSSDIVAW 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295
		ER_PDI_fam	166..500	CDD:273457	87/249 (35%)
		PDI_a_PDIR	272..373	CDD:239295	40/116 (34%)
		PDI_a_PDIR	397..498	CDD:239295	45/104 (43%)
pdi-6	NP_509190.1	PDI_a_P5	25..127	CDD:239299	36/106 (34%)
		PDI_a_P5	165..269	CDD:239299	45/104 (43%)
		P5_C	278..407	CDD:239281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810