Protein Alignment CG9302 and C14B9.2

DIOPT Version :10

• Sequence 1: NP_609645.2
• Gene: CG9302 / 34750
• FlyBaseID: FBgn0032514
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_498775.2
• Gene: C14B9.2 / 176147
• WormBaseID: WBGene00015752
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 145/628 - (23%)
• Similarity: 222/628 - (35%)
• Gaps: 269/628 - (42%)

  Fly   114 YDRQ------LSVSSMITFMRDPSGD-LPWEEDPAGKDVLHFSDAASFTKHLRKDIRPMLVMFYV 171
            :||:      |...|.:....|.|.| |.:|.|   :.|:..:| .:|...|:|: ..:||.||.
 Worm     3 FDRRFFALVVLLCVSAVRSTEDASDDELNYEMD---EGVVVLTD-KNFDAFLKKN-PSVLVKFYA 62

  Fly   172 PWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRFTY 236
            ||||.||.:.|||.|||:::......:.|.:..|      :.|.|.|.|:|||.::::||....|
 Worm    63 PWCGHCKHLAPEYEKASSKVSIPLAKVDATVETE------LGKRFEIQGYPTLKFWKDGKGPNDY 121

  Fly   237 EGENNKEALVSFM---LNPNAKPTPKPKEPEWSADTNSEIVHLTSQGFEPALKDEKSALVMFYAP 298
            :|..::..:|.::   ::||.||.|:            |:|.||::.|:..:.:.:..||.||||
 Worm   122 DGGRDEAGIVEWVESRVDPNYKPPPE------------EVVTLTTENFDDFISNNELVLVEFYAP 174

  Fly   299 WCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEKYKVKGYPTVKFFSNGVFKFEVN- 362
            ||||||::.|||||||.::|.:.....|..:|||.|..:..||.|.||||:|...|| .:|:.|
 Worm   175 WCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNG-RRFDYNG 238

  Fly   363 VREASKIVEFMRDPKEPPPPPPPE----------------------------------------- 386
            .|||:.|:::|.|..:|.....|:
 Worm   239 PREAAGIIKYMTDQSKPAAKKLPKLKDVERFMSKDDVTIIGFFATEDSTAFEAFSDSAEMLREEF 303

  Fly   387 ------------KSW-------------------------------------------------- 389
                        |.|
 Worm   304 KTMGHTSDPAAFKKWDAKPNDIIIFYPSLFHSKFEPKSRTYNKAAATSEDLLAFFREHSAPLVGK 368

  Fly   390 --------------------------------------------------------EEEEDSKE- 397
                                                                    :|||.:||
 Worm   369 MTKKNAATRYTKKPLVVVYYNADFSVQYREGSEYWRSKVLNIAQKYQKDKYKFAVADEEEFAKEL 433

  Fly   398 --------------VLF--------LDDDNFSSTL--------------KRKKH----------- 415
                          |:|        ::.|.|...|              |.|.|
 Worm   434 EELGLGDSGLEHNVVVFGYDGKKYPMNPDEFDGELDENLEAFMKQISSGKAKAHVKSAPAPKDDK 498

  Fly   416 ---------------------ALVMFYAPWCGHCKHTKPEFTAAATAL-QDDPRIAFVAIDCTKL 458
                                 .|:.||||||||||..:.::...|.|| :..|.:....:|.| :
 Worm   499 GPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDAT-I 562

  Fly   459 AALCAKYNVRGYPTILYFSYLKTK---LDYNGGRTSKDFIAYM 498
            ....:::.|.|:||| ||:....|   :.|:|.|..:|...:|
 Worm   563 NDAPSQFAVEGFPTI-YFAPAGKKSEPIKYSGNRDLEDLKKFM 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365	5/22 (23%)
		PDI_a_PDIR	144..249	CDD:239295	35/104 (34%)
		PDI_a_PDIR	272..373	CDD:239295	46/101 (46%)
		PDI_a_PDIR	397..498	CDD:239295	38/173 (22%)
C14B9.2	NP_498775.2	pdi_dom	41..138	CDD:273454	34/104 (33%)
		ER_PDI_fam	147..616	CDD:273457	95/473 (20%)