Protein Alignment CG9302 and pdia4

DIOPT Version :10

• Sequence 1: NP_609645.2
• Gene: CG9302 / 34750
• FlyBaseID: FBgn0032514
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_002941424.1
• Gene: pdia4 / 100491067
• XenbaseID: XB-GENE-5892157
• Length: 632
• Species: Xenopus tropicalis
• Alignment Length: 648
• Identity: 140/648 - (21%)
• Similarity: 207/648 - (31%)
• Gaps: 284/648 - (43%)

  Fly    72 GTGTMLLLDCGQQDRKKLCKKLKVSPDPYAIKHYKDGDFHKDYDRQLSVSSMITFMRDPSGDLPW 136
            |...:.::.|.|:::         .|:    :|..|.|..:|.          |.::|.:|
 Frog    14 GLAHVAIITCNQEEK---------GPE----EHSDDEDTSEDE----------TEVKDENG---- 51

  Fly   137 EEDPAGKDVLHFSDAASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAA 201
                    ||..:|....|....|||  :|:.||.||||.||:..|||.|.::.|......|..|
 Frog    52 --------VLVLTDKNFDTFITDKDI--VLLEFYAPWCGHCKQFVPEYEKIASALNQNDPPIPVA 106

  Fly   202 MNVERQENAPIRKMFNITGFPTLIYFENGKLRFTYEGENNKEALVSFMLNPNAKPTPKPKE---P 263
             .::..|...:...::|:|:||:...:.|: ...|:|...:||:|:           |.||   |
 Frog   107 -KIDATEATDVAGRYDISGYPTIKILKKGQ-PIDYDGARTQEAIVT-----------KVKEIAQP 158

  Fly   264 EWSADTNSEIVHLTSQGFEPALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAA 328
            :|.....:.|| ||...|:..:.|....||.||||||||||::.|||||||.|:.::..|..||.
 Frog   159 DWKPPPEATIV-LTKDNFDEVVSDADIILVEFYAPWCGHCKKLAPEYEKAAQELSKRSPPIPLAK 222

  Fly   329 LDATKEPSIAEKYKVKGYPTVKFFSNG-VFKFEVNVREASKIVEFMRDPKEPPPPP--------- 383
            :|||.|.|:..||.|.|:||:|.|..| ||.:. ..||...||::|.:...||...
 Frog   223 VDATVESSLGSKYGVTGFPTLKIFRKGKVFDYN-GPREKYGIVDYMTEQAGPPSKQIQAVKQVHE 286

  Fly   384 ------------------------------------------------------------PPEKS 388
                                                                        .|||.
 Frog   287 FFRDGDDVGILGVFSDEKDRAYHLYQDAANNLREDYKFYHTFSSEIFNFLKVSPGQLVVMQPEKF 351

  Fly   389 WEEEEDSKEVLFLDD-------------------------------------------------- 403
            ..:.|..|.:|...|
 Frog   352 QSKYEAKKYILSFKDSTTAADIKQHISEHSLPLVGHRKNSNEAKRYSKRPIVVVYYSVDFGFDYR 416

  Fly   404 ---------------------------DNFSSTLK-------------------RKKHA------ 416
                                       |::::.||                   .||:|
 Frog   417 TATQYWRSKILEVAKDFSEYTFAIANEDDYATELKDLGLSDSGEEVNVAIFDASGKKYAKEPEEF 481

  Fly   417 -----------------------------------------------------LVMFYAPWCGHC 428
                                                                 |:.|||||||||
 Frog   482 DSDGLREFVMAFKKGKLTPIIKSQPVPKNNKGPVKVVVGKTFDQIVMDPKSDVLIEFYAPWCGHC 546

  Fly   429 KHTKPEFTAAATALQDDPRIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTK---LDYNGG 488
            |..:|.:.......:....:....:|.|.......||...|:||| ||:....|   :.::||
 Frog   547 KSLEPIYNDLGKKYRSAEGLIIAKMDATANDITSDKYKAEGFPTI-YFAPRNNKQNPIKFSGG 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365	10/58 (17%)
		PDI_a_PDIR	144..249	CDD:239295	34/104 (33%)
		PDI_a_PDIR	272..373	CDD:239295	49/101 (49%)
		PDI_a_PDIR	397..498	CDD:239295	33/250 (13%)
pdia4	XP_002941424.1	pdi_dom	55..154	CDD:273454	33/113 (29%)
		ER_PDI_fam	165..624	CDD:273457	90/447 (20%)