DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6565 and Stard7

DIOPT Version :9

Sequence 1:	NP_001285891.1	Gene:	CG6565 / 34749	FlyBaseID:	FBgn0032513	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_647469.2	Gene:	Stard7 / 99138	MGIID:	2139090	Length:	373	Species:	Mus musculus

Alignment Length:	392	Identity:	110/392 - (28%)
Similarity:	171/392 - (43%)	Gaps:	84/392 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TLRAW-------------SYQCESIFAQRSRRVQQLFSFYQSVYGTQGLKQLWRAYYRRELQPPL 68
            ||.||             :.||..:...|.||.||:...|..:|.......|...::||     |
Mouse     9 TLAAWLAGARGGGLLSALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRR-----L 68

  Fly    69 RG------MVMSAVGLVGLNIKRMGSDGFDWNKERLALSNFDLCRRDIEFINALPNNQLCDRCQA 127
            ||      ::|:|:           |..|.|::||:.....   :|.|.              :.
Mouse    69 RGRPGHASVLMAAL-----------SGVFVWDEERIQEEEL---QRSIN--------------EM 105

  Fly   128 KKMKYCYCQLGNQRCKKG-QSQPSTSKEAETDPDTSISNCLRPLDLDVRNAPAGTVRIQAQDDQK 191
            |:::    ::.|.....| ::.|...|                       :|||........::.
Mouse   106 KRLE----EMSNIFQSSGVENYPPEPK-----------------------SPAGGNEKSKDKEEP 143

  Fly   192 WEPYFSKNEFSIWRRQ-ERSSLYSYKVYARFDDITADDFLHVQTDLDYRRQWDDTALRLELISED 255
            ||....|..|.:|||. ..:.||.|:|:..:.|:|...|.:||.|.:||::||...::||:|..|
Mouse   144 WEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERD 208

  Fly   256 PVPGSNSHLIYWEMQWPRLFANRDYVYCRRYIKDDNKKLIFICNRGATHNTYPALSGKVRVTDYW 320
            .|.|  |.:::|...:|....:|||||.|||..|....::.:.:|...|.:.|.....|||..|.
Mouse   209 AVSG--SEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYE 271

  Fly   321 SLMVIKPFRGFHEPGLHFVLTYFDDPGIPIPQNIKSWVTQKQMPEFLTKMYVATKNYACSRAIKM 385
            |.|||:|.:.|.|.|..::|||.|:|....|:...||:....||:||.|:::||.. |.:..||:
Mouse   272 SQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLK-AKNMEIKV 335

  Fly   386 KD 387
            ||
Mouse   336 KD 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6565	NP_001285891.1	START_STARD7-like	170..377	CDD:176920	72/207 (35%)
Stard7	NP_647469.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..141		6/45 (13%)
		START_STARD7-like	139..328	CDD:176920	69/191 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	347..373
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842810
Domainoid	1	1.000	130	1.000	Domainoid score	I5193
eggNOG	1	0.900	-	-		E1_KOG2761
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32463
Inparanoid	1	1.050	150	1.000	Inparanoid score	I4362
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47410
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004152
OrthoInspector	1	1.000	-	-		oto93932
orthoMCL	1	0.900	-	-		OOG6_107016
Panther	1	1.100	-	-	LDO	PTHR19308
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7794
SonicParanoid	1	1.000	-	-		X5180
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790