DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6523 and GRX3

DIOPT Version :9

Sequence 1:	NP_609641.1	Gene:	CG6523 / 34745	FlyBaseID:	FBgn0032509	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_010383.4	Gene:	GRX3 / 851672	SGDID:	S000002505	Length:	250	Species:	Saccharomyces cerevisiae

Alignment Length:	238	Identity:	83/238 - (34%)
Similarity:	126/238 - (52%)	Gaps:	34/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPVVNVSAAEEYQKYIN----ADKTTVALFAAEWAEQCGQVKDALEELA-KITGEKLQFISLNAE 60
            |||:.::..|:: .|:.    .||..|..|...|||.|..:|...|.:: :.:...:.|:|::|:
Yeast     1 MPVIEINDQEQF-TYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDAD 64

  Fly    61 QFPEISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAAATGQTLEE----- 120
            :..|||...:|.|||..|...||:.:..:.|.|.....:..:....:.:|.::...|:|.
Yeast    65 ENSEISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLEDCKNSVNSGSSQTHTMENANVNE 129

  Fly   121 -----------------------RLKALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYE 162
                                   ||..|:|.||:|:||||..:.|:||||:||:||:.|..:.:.
Yeast   130 GSHNDEDDDDEEEEEETEEQINARLTKLVNAAPVMLFMKGSPSEPKCGFSRQLVGILREHQVRFG 194

  Fly   163 TFDILGDEEVRQGLKTYSDWPTYPQVYVKGELIGGLDIIKELL 205
            .||||.||.|||.||.:|:|||:||:|:.||..||||||||.|
Yeast   195 FFDILRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIKESL 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6523	NP_609641.1	TRX_PICOT	8..102	CDD:239282	27/98 (28%)
CG6523	NP_609641.1	GRX_PICOT_like	122..211	CDD:239326	49/84 (58%)
GRX3	NP_010383.4	TRX_PICOT	9..106	CDD:239282	27/97 (28%)
GRX3	NP_010383.4	GRX_PICOT_like	154..238	CDD:239326	49/84 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346189
Domainoid	1	1.000	86	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E1_COG0278
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I1070
Isobase	1	0.950	-	0	Normalized mean entropy	S1091
OMA	1	1.010	-	-		QHG53575
OrthoFinder	1	1.000	-	-		FOG0003496
OrthoInspector	1	1.000	-	-		otm46620
orthoMCL	1	0.900	-	-		OOG6_101660
Panther	1	1.100	-	-	LDO	PTHR10293
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2861
TreeFam	1	0.960	-	-
	14	13.710