DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6523 and glrx3

DIOPT Version :9

Sequence 1:	NP_609641.1	Gene:	CG6523 / 34745	FlyBaseID:	FBgn0032509	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001005950.1	Gene:	glrx3 / 449777	ZFINID:	ZDB-GENE-041010-22	Length:	326	Species:	Danio rerio

Alignment Length:	220	Identity:	107/220 - (48%)
Similarity:	141/220 - (64%)	Gaps:	10/220 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVNVSAAEEYQKY-----INADKTTVALFAAEWAEQCGQVKDALEELAKITGEKLQFISLNAEQF 62
            :.|.:.|...|::     .|:...||..|.|.||.||.|:.|.:.|||| ..:...|:.|.||..
Zfish     1 MANFTDAASLQQFDELLKNNSKSLTVVHFHAPWAPQCSQMNDVMAELAK-EHKHTMFVKLEAEAV 64

  Fly    63 PEISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAAATG----QTLEERLK 123
            ||:|.|::|.:|||.:||..|..:||:||.....::.|.::|......|...|    :.|.:|||
Zfish    65 PEVSEKYEITSVPTFLFFKGGEKIDRLDGAHAPELTNKVQRLGSGGGGAVGAGDVPKEDLNQRLK 129

  Fly   124 ALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYETFDILGDEEVRQGLKTYSDWPTYPQV 188
            .|||.||.|:||||....||||||:|:|.|:.:.|:.|.:||||.||||||||||||:|||||||
Zfish   130 RLINAAPCMLFMKGSPQEPRCGFSRQIIQILKDHNVQYSSFDILSDEEVRQGLKTYSNWPTYPQV 194

  Fly   189 YVKGELIGGLDIIKELLANNELEST 213
            ||.|||||||||:|||:.:.|||:|
Zfish   195 YVSGELIGGLDIVKELVESGELENT 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6523	NP_609641.1	TRX_PICOT	8..102	CDD:239282	37/98 (38%)
CG6523	NP_609641.1	GRX_PICOT_like	122..211	CDD:239326	61/88 (69%)
glrx3	NP_001005950.1	TRX_PICOT	9..104	CDD:239282	36/95 (38%)
		GRX_PICOT_like	128..217	CDD:239326	61/88 (69%)
		GRX_PICOT_like	230..319	CDD:239326
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594970
Domainoid	1	1.000	101	1.000	Domainoid score	I6918
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3667
OMA	1	1.010	-	-		QHG53575
OrthoDB	1	1.010	-	-		D1449534at2759
OrthoFinder	1	1.000	-	-		FOG0003496
OrthoInspector	1	1.000	-	-		oto38634
orthoMCL	1	0.900	-	-		OOG6_101660
Panther	1	1.100	-	-	LDO	PTHR10293
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R497
SonicParanoid	1	1.000	-	-		X2861
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940