DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6523 and Glrx3

DIOPT Version :9

Sequence 1:	NP_609641.1	Gene:	CG6523 / 34745	FlyBaseID:	FBgn0032509	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_075629.2	Gene:	Glrx3 / 30926	MGIID:	1353653	Length:	337	Species:	Mus musculus

Alignment Length:	220	Identity:	106/220 - (48%)
Similarity:	145/220 - (65%)	Gaps:	15/220 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVNVSAAEEYQKYINADKT---TVALFAAEWAEQCGQVKDALEELAKITGEKLQFISLNAEQFPE 64
            ||.|.:|:::::.:.. ||   .|..|.|.||.||.|:.|.:.|||| ....:.|:.|.||..||
Mouse    15 VVEVGSAQQFEELLRL-KTKSLLVVHFWAPWAPQCVQMNDVMAELAK-EHPHVSFVKLEAEAVPE 77

  Fly    65 ISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAA---ATGQTLEE----RL 122
            :|.|::|.:|||.:||.....|||:||.....:   :||:..:.||.|   :|.:.|:|    ||
Mouse    78 VSEKYEISSVPTFLFFKNSQKVDRLDGAHAPEL---TKKVQRHVSSGAFPPSTNEHLKEDLSLRL 139

  Fly   123 KALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYETFDILGDEEVRQGLKTYSDWPTYPQ 187
            |.|.:.||.|:||||....||||||||::.|:::.|:.:.:|||..||||||||||||:||||||
Mouse   140 KKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQ 204

  Fly   188 VYVKGELIGGLDIIKELLANNELES 212
            :||.|||||||||||||.|:.||::
Mouse   205 LYVSGELIGGLDIIKELEASEELDT 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6523	NP_609641.1	TRX_PICOT	8..102	CDD:239282	35/96 (36%)
CG6523	NP_609641.1	GRX_PICOT_like	122..211	CDD:239326	58/88 (66%)
Glrx3	NP_075629.2	TRX_PICOT	20..115	CDD:239282	37/99 (37%)
		GRX_PICOT_like	139..227	CDD:239326	57/87 (66%)
		GRX_PICOT_like	241..329	CDD:239326
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849376
Domainoid	1	1.000	100	1.000	Domainoid score	I7019
eggNOG	1	0.900	-	-		E1_COG0278
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I3832
Isobase	1	0.950	-	0	Normalized mean entropy	S1091
OMA	1	1.010	-	-		QHG53575
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003496
OrthoInspector	1	1.000	-	-		oto92534
orthoMCL	1	0.900	-	-		OOG6_101660
Panther	1	1.100	-	-	LDO	PTHR10293
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R497
SonicParanoid	1	1.000	-	-		X2861
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.740