DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9377 and modSP

DIOPT Version :9

Sequence 1:	NP_609640.1	Gene:	CG9377 / 34743	FlyBaseID:	FBgn0032507	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	91/406 - (22%)
Similarity:	145/406 - (35%)	Gaps:	121/406 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SKVCGPEK-------HCVPYEQCNEGLMVDGKFYPDRSRTTLDENCHYMEKCCNIPDKLPTPKI- 78
            |..|...|       .||.|  |:.....||  |..::..|  .|...:|  |..|...|..::
  Fly   267 SSYCAKNKWSTSTIPKCVKY--CSTAGEFDG--YSTKALCT--HNGQQVE--CRKPFHPPGTEVK 323

  Fly    79 -----------PEEMMSCPCGGRHDLWYYLRPLGYKQQEAKFGEF-------------------P 113
                       |...|.|..||     |:.|  |.::.|...|:.                   |
  Fly   324 FVCSTGFKTLSPLPEMRCMKGG-----YWNR--GRQRCEQDCGQLATPIKQFSSGGYTINNTVVP 381

  Fly   114 WLVAVY----GSDTYL-CSGALITPLAVITTAHCVQNS------EMEKVRLLAGEWDAAVELEPQ 167
            |.|.:|    ..|.:. |.|:|:||..|||.||||.:.      ..:..|::|.::..... |..
  Fly   382 WHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYG-ETT 445

  Fly   168 PHQQRSVVETL-VHP-------NYTQMPLAHNIAILLVDKEKPFQLAPNVQPICLPPPRIMYNYS 224
            |.::|..|..: :.|       ||.|     ::|:|.:|  :||:|:..::|||:.........|
  Fly   446 PEEKRRDVRLIEIAPGYKGRTENYYQ-----DLALLTLD--EPFELSHVIRPICVTFASFAEKES 503

  Fly   225 -----QCYVSGWQRSDFGRAAILPKRWTLYVLPP-----DQCRTKLR--------LSLLGRRHAH 271
                 |...:||.         :..:..|..:|.     ..||..||        :...|:
  Fly   504 VTDDVQGKFAGWN---------IENKHELQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGK---- 555

  Fly   272 NDSLLCAGGDKGDFVCGDVDMTAVPLMCPLSGHDDRFHLAGLLTRTARCDG-PQLLGIYTNVKLY 335
              ||.|.|...|.|.      :.:|.....:.:..|..|.|:::.....|. ...|.:.||::.:
  Fly   556 --SLACQGDSGGGFT------SELPTNAFSTWNTARHFLFGVISNAPNADQCAHSLTVMTNIQHF 612

  Fly   336 RQWIDLKLRERNLDIR 351
            ...| |....|:::.|
  Fly   613 EDMI-LNAMNRSVETR 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9377	NP_609640.1	Tryp_SPc	105..340	CDD:238113	63/291 (22%)
CG9377	NP_609640.1	Tryp_SPc	105..339	CDD:214473	63/290 (22%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	3/16 (19%)
		Sushi	309..354	CDD:278512	12/53 (23%)
		Tryp_SPc	371..616	CDD:214473	61/273 (22%)
		Tryp_SPc	371..591	CDD:304450	57/248 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030