Protein Alignment CG9377 and PRSS50

DIOPT Version :10

• Sequence 1: NP_609640.1
• Gene: CG9377 / 34743
• FlyBaseID: FBgn0032507
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 63/265 - (23%)
• Similarity: 117/265 - (44%)
• Gaps: 54/265 - (20%)

  Fly   103 KQQEAKFGEFPWLVAVYGSDTYLCSGALITPLAVITTAHC-VQNSEMEKVRLLAGEWDAAVELEP 166
            :..||....:||:|:|..:.|::|:|.:|....|:|.||| :....:..|| :...|   ::...
Human   115 RDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVR-VGSPW---IDQMT 175

  Fly   167 QPHQQRSVVETLVHPNY------TQMPLAHNIAILLVDKEKPFQLAPNVQPICLP-PPRIMYNYS 224
            |......|::.::|..|      :.:..|::|.:|.:.:|  .:.:..|:||||| ...::.::|
Human   176 QTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQE--LKYSNYVRPICLPGTDYVLKDHS 238

  Fly   225 QCYVSGW--QRSDFGRAAILPKRWTLYVLPPDQCRT--KLRLSLLGRRHAHN------------- 272
            :|.|:||  .::|        ..|       .|.||  :..:.:|..:...|
Human   239 RCTVTGWGLSKAD--------GMW-------PQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQ 288

  Fly   273 ---DSLLCAGGDKGDFVCGDVDMTAVPLMCPLSGHDDRFHLAGLLTRTARCDGPQLLGIYTNVKL 334
               ..::||.....:..|  .::|..||:|.:.|   .::|.||::..|.|...:...||..|..
Human   289 IIKSQMMCAEDTHREKFC--YELTGEPLVCSMEG---TWYLVGLVSWGAGCQKSEAPPIYLQVSS 348

  Fly   335 YRQWI 339
            |:.||
Human   349 YQHWI 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9377	NP_609640.1	PRK06406	<19..>80	CDD:235796
		Tryp_SPc	105..339	CDD:214473	61/261 (23%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	61/260 (23%)