DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9377 and F9

DIOPT Version :9

Sequence 1:	NP_609640.1	Gene:	CG9377 / 34743	FlyBaseID:	FBgn0032507	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	246	Identity:	67/246 - (27%)
Similarity:	114/246 - (46%)	Gaps:	23/246 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 QEAKFGEFPWLVAVYGSDTYLCSGALITPLAVITTAHCVQNSEMEKVRLLAGEWDAAVELEPQPH 169
            ::||.|:|||.|.:.|.....|.|:::....::|.||||:..  .|:.::|||.:  :|......
Human   231 EDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETG--VKITVVAGEHN--IEETEHTE 291

  Fly   170 QQRSVVETLVHPNYTQMPLAHNIAILLVDKEKPFQLAPNVQPICLPP---PRIMYNYSQCYVSGW 231
            |:|:|:..:.|.||......:|..|.|::.::|..|...|.|||:..   ..|...:...|||||
Human   292 QKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGW 356

  Fly   232 QR-SDFGRAAILPKRWTLYVLPPDQCRTKLRLSLLGRRHAHNDSLLCAGGDKG--DFVCGDVDMT 293
            .| ...||:|::.:...:.::....|....:.::.       :::.|||..:|  |...||   :
Human   357 GRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIY-------NNMFCAGFHEGGRDSCQGD---S 411

  Fly   294 AVPLMCPLSGHDDRFHLAGLLTRTARCDGPQLLGIYTNVKLYRQWIDLKLR 344
            ..|.:..:.|..   .|.|:::....|......||||.|..|..||..|.:
Human   412 GGPHVTEVEGTS---FLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9377	NP_609640.1	Tryp_SPc	105..340	CDD:238113	65/240 (27%)
CG9377	NP_609640.1	Tryp_SPc	105..339	CDD:214473	64/239 (27%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	66/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910