Protein Alignment CG31729 and DNF3

DIOPT Version :9

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_013885.1
• Gene: DNF3 / 855197
• SGDID: S000004772
• Length: 1656
• Species: Saccharomyces cerevisiae
• Alignment Length: 1414
• Identity: 350/1414 - (24%)
• Similarity: 566/1414 - (40%)
• Gaps: 435/1414 - (30%)

  Fly   214 RARTVNLGRVNTEKFP----PNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRI 274
            :|.|...|.:..|:|.    .|.|.:.:|.|.:|||..|:.||....|.||.::|:.|.||....
Yeast   120 QAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWST 184

  Fly   275 GYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHE---------------------------VNSQ 312
            ...||...||...:.:::.|||.||.|||:.|.|                           |:|.
Yeast   185 TGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSST 249

  Fly   313 KYKRLSS---------------------TNISGYEMVPS-----------SKLKVGDVIIVEKNE 345
            .|...|:                     |:.:.:|::.:           .||:|||.:::.:::
Yeast   250 AYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDD 314

  Fly   346 RVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSR-DSELHSIDASFYVEKPQND 409
            .|||||:||.....:...||.|..|||||:.|.:...|...||:: .|.|.:|:|...||.|..|
Yeast   315 WVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNID 379

  Fly   410 IHSFIATFCMADGSEDT----GLSVENTLWANTVVA-AGTATGIVIYTGCETRSVMNN-SQPRSK 468
            :::|.....:.:...||    .|..:|.::..:::. .....|:||::|.||:..||. ..||:|
Yeast   380 LYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTK 444

  Fly   469 VGLLDMEINGLTKVLFCAVLGLSLV-----MMMLKGF---GGPWYRY---------MFRFVLLFS 516
            ...|..:||.:...:...|..:||.     ::..|.:   ...||.:         :..|:::::
Yeast   445 APKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVAPTIMSFIIMYN 509

  Fly   517 YIIPISLRVNLDMGKAFYSWQMQNDSNIQGTVV------RSTTIPEELGRISYVLTDKTGTLTQN 575
            .:||:||.|.:::.|...|..|:.|.::.....      |:.||.||||::||:.:|||||||.|
Yeast   510 TVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDN 574

  Fly   576 EMVFKK--------IHLGIVSHDADTFH---------------HIGQMIQKLS---GNILQ---- 610
            :|:|:|        :|...:.:..|.|.               |.|..|..:|   .|:|.
Yeast   575 KMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSIDVVSIGDQNVLDRLGF 639

  Fly   611 -----------------------QQQGSLSSSSSGGDSTKPMMFGNR------------------ 634
                                   :.:|:.|:..:|..|.: .:||..
Yeast   640 SDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMR-SLFGKDNSHLSKQASVISPSETFS 703

  Fly   635 -------------MRRPEGWREWEA---VRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTK 683
                         .|.|......:|   ..:|||||:..|  ....|.|:...|.
Yeast   704 ENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHSCLP--KKTHNESIGEDSI---------- 756

  Fly   684 SVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILL-HYQ 747
                           :||::||||:|||.....:|..::.|:...:|::......|.:..| :|:
Yeast   757 ---------------EYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDGEAKLENYE 806

  Fly   748 ILQLFPFTSESKRMGIIVR-ESKTGQITFYLKGAD-VVM-------------------------- 784
            ||....|.|:.|||.::|| .::..|:....|||| |:|
Yeast   807 ILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKERKDA 871

  Fly   785 ----------------------------------------------------------------- 784
                                                                             
Yeast   872 EAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAVRKSLSMKNSRTRDPEKQIDSID 936

  Fly   785 -------------SSIV------------------------------------------QYNDWL 794
                         .|:|                                          .|:..:
Yeast   937 QFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRISIDGTHFPNNNVPIDTRKEGLQHDYDTEI 1001

  Fly   795 SEESGN--------------------MAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRV 839
            .|..|:                    .:.|||||||.|.|.:...||.::..||:.|:.|:|||.
Yeast  1002 LEHIGSDELILNEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRK 1066

  Fly   840 AKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLI 904
            .||......:|..|.||.:|.:||:||:.|...:|.:|.||:::|||||||.|||..|..|..||
Yeast  1067 IKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLI 1131

  Fly   905 GRNQGLHVLRSVKTRTDAH---------QELNSFRRKQGH----ALVISGESLEVC--LQYYRPE 954
            .....:.:|    |.||.:         ||::|     |:    .:||.|.::.:.  ...|...
Yeast  1132 KDYSTVVIL----TTTDENIISKMNAVSQEVDS-----GNIAHCVVVIDGATMAMFEGNPTYMSV 1187

  Fly   955 FLELATASPAVVCCRCSPTQKAQVVALIQKHTGKR--TCAVGDGGNDVSMIQQADAGVGIEGREG 1017
            |:||.|.:.:|:|||.||:|||.:|:.| ::|...  |.|:|||.||::|||.||.||||.|:||
Yeast  1188 FVELCTKTDSVICCRASPSQKALMVSNI-RNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEG 1251

  Fly  1018 RQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALY 1082
            .|||...|:||.||..:.|||.:|||.:|.|::.......::.:.....|.::......|..:||
Yeast  1252 LQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLY 1316

  Fly  1083 QGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYK--DLSKGRSLSYKTFFIWVLISIYQ 1144
            :.:.:..::||:|..||..: :.::|:...|.:|.||||.  .||:|  .::..|..||:::...
Yeast  1317 EPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQG--FNWLIFMEWVILATTN 1379

  Fly  1145 G------GVIMYGALILFVDEFIHIVAISFS---ALIMTELIMVALTVRTWHRLMVLAELFSLAL 1200
            .      .|:|:|...|..:....:..|:|:   |||..:...|.:..|.|  |...:.:.|...
Yeast  1380 SLIITFLNVVMWGMSSLSDNTMYPLGLINFTAIVALINVKSQFVEMHNRNW--LAFTSVVLSCGG 1442

  Fly  1201 YLI---SLAVLHEYFDWEFIWSYDF---------LWKVSLITLVSCLPL 1237
            :|:   :|.:|:. .|..:..:|.|         .|..||:  ::.||:
Yeast  1443 WLVWCCALPILNN-TDQIYDVAYGFYNHFGKDITFWCTSLV--LALLPI 1488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	18/55 (33%)
		ATPase-Plipid	228..1252	CDD:273734	346/1400 (25%)
		E1-E2_ATPase	323..525	CDD:278548	63/236 (27%)
		Cation_ATPase	<704..783	CDD:289987	27/81 (33%)
		HAD_like	<975..1019	CDD:304363	24/45 (53%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	61/241 (25%)
DNF3	NP_013885.1	P-type_ATPase_APLT_Dnf-like	140..1386	CDD:319770	320/1285 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910