DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31729 and AT1G26130

DIOPT Version :9

Sequence 1:	NP_609634.1	Gene:	CG31729 / 34736	FlyBaseID:	FBgn0051729	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_001185096.1	Gene:	AT1G26130 / 839154	AraportID:	AT1G26130	Length:	1185	Species:	Arabidopsis thaliana

Alignment Length:	1208	Identity:	344/1208 - (28%)
Similarity:	552/1208 - (45%)	Gaps:	208/1208 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 RRKSKSRSIGNVCKLCLCSCWRKWFRPRELRARTVNLGRV-----------NTEKFPPNEIRNQK 237
            |||.|.:    :.||...:..:..|:|...:.......||           .:..:..|.:|..|
plant     8 RRKRKIQ----LSKLFTLTGAKACFKPDHSKIGRSGFSRVVFCNQPDSPEAESRNYCDNYVRTTK 68

  Fly   238 YNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWG---PLGFVLMVTICREAVDD 299
            |...||||..||||||...|.|||::.:..|.|..    |||...   ||.||::.|:.:|.|:|
plant    69 YTLATFLPKSLFEQFRRVANFYFLVVGILSFTPLA----PYTAVSAIVPLTFVILATMFKEGVED 129

  Fly   300 LRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVF 364
            .||.|:|.|||::|. |:...| ..:::.....|:|||::.|||||..||||:||.:|......:
plant   130 WRRKQQDIEVNNRKV-RVHRGN-GNFDLREWKTLRVGDILKVEKNEFFPADLVLLSSSYEDAVCY 192

  Fly   365 VRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSEDTGLS 429
            |.|..|||||:.|.:..:..|..|..:......:|....|.|..:::||:.|..:.  .|...||
plant   193 VETMNLDGETNLKLKQGLEVTLSLREELNFRDFEAFIKCEDPNANLYSFVGTMDLK--GEKYPLS 255

  Fly   430 VENTLWANTVVA-AGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLV 493
            .:..|...:.:. .....|:||:||.:|:.|.|::.|.||..:::.:::.:..::|..|..|:..
plant   256 PQQLLLRGSKLRNTDYIYGVVIFTGPDTKVVQNSTDPPSKRSMIERKMDKIIYLMFLMVFSLAFF 320

  Fly   494 MMML----------KGFGGPWY-----------------RYMFRF---VLLFSYIIPISLRVNLD 528
            ..:|          .|....||                 ..::.|   ::|.||.|||||.|:::
plant   321 GSVLFGIWTRDDFQNGVMERWYLKPDDSSIFFDPKRAPMAAIYHFLTALMLNSYFIPISLYVSIE 385

  Fly   529 MGKAFYSWQMQNDSNI------QGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIV 587
            :.|...|..:..|.::      :....|::.:.||||::..:|:|||||||.|.|.|.|..:
plant   386 IVKVLQSIFINQDIHMYYEEADKPAHARTSNLNEELGQVGTILSDKTGTLTCNSMEFIKCSI--- 447

  Fly   588 SHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDST------KPMMFGNRMRRPE----GW- 641
               |.|.:..|....:::   :.:::||...:.|.|:||      :|.:.|...|...    .|
plant   448 ---AGTAYGRGVTEVEMA---MDKRKGSALVNQSNGNSTEDAVAAEPAVKGFNFRDERIMDGNWV 506

  Fly   642 REWEA------VRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQY 700
            .|..|      .:.||:||.|.| ..|||...:|                              |
plant   507 TETHADVIQKFFQLLAVCHTVIP-EVDEDTGKIS------------------------------Y 540

  Fly   701 QAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIV 765
            :|.||||.|.|....::|.....|...|::::.........:...|.:|.:..|:|..|||.:||
plant   541 EAESPDEAAFVIAARELGFEFFTRTQTTISVRELDLVTGERVERLYSVLNVLEFSSSKKRMSVIV 605

  Fly   766 RESKTGQITFYLKGADVVM-----SSIVQYNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFE 825
            :: :.|::....||||.||     .|..:|.....:.....|..|||||::|.:.|.|.:|..|.
plant   606 QD-QDGKLLLLCKGADSVMFERLSESGRKYEKETRDHVNEYADAGLRTLILAYRELDENEYEVFT 669

  Fly   826 TRYNAARLSIT-DRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGD 889
            .|.:.|:.|:: ||.|.:..|||.:|:.|.||..|.|||:||..|...:..|..||:::|:||||
plant   670 ERISEAKNSVSADREALIDEVTEKIEKNLVLLGATAVEDKLQNGVPDCINKLAQAGIKIWVLTGD 734

  Fly   890 KLETACCIAKSSQLIGRNQG-------------------------------LHVLRSVKTRTDAH 923
            |:|||..|..:..|:.|:..                               ||.:.|.|.:..|
plant   735 KMETAINIGFACSLLRRDMKQIIINLETPEIQQLEKSGEKDAIAAALKENVLHQITSGKAQLKA- 798

  Fly   924 QELNSFRRKQGHALVISGESLEVCLQY-YRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTG 987
                |....:..||:|.|:||...|:. .:..|||||....:|:|||.||.|||.|..|::..:|
plant   799 ----SGGNAKAFALIIDGKSLAYALEEDMKGIFLELAIGCASVICCRSSPKQKALVTRLVKTGSG 859

  Fly   988 KRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAAL 1052
            :.|.|:|||.|||.|:|:||.||||.|.||.||.::.|.:|.||.::.:|||:||...|:|.:.:
plant   860 QTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYRRISKM 924

  Fly  1053 SQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTY 1116
            ..:..::.:.......::.|....|:...|..:.:..||..:|..||..| :.|||:::...:.:
plant   925 ICYFFYKNITFGFTLFLYEAYTSFSATPAYNDWYLSLYSVFFTSLPVICLGIFDQDVSAPFCLKF 989

  Fly  1117 PELYKDLSKGRSLSYKTFFIWVL------ISIY------------------QGGVIMYGAL---I 1154
            |.||::..:....|::....|:.      |.|:                  .|..|:.|.:   :
plant   990 PVLYQEGVQNLLFSWRRILSWMFHGFCSAIIIFFLCKTSLESQAFNHEGKTAGRDILGGTMYTCV 1054

  Fly  1155 LFVDEFIHIVAISFSALIMTELIMVALTVRTWHR-LMVLAEL---FSLALYLISLAVLHEYFDWE 1215
            ::|.....::.||:..||  :.::|..:|..|:. |||...|   .|...|::.|..|..
plant  1055 VWVVSLQMVLTISYFTLI--QHVVVWGSVVIWYLFLMVYGSLPIRMSTDAYMVFLEALAP----- 1112

  Fly  1216 FIWSYDFLWKVSL-ITLVSCLPLYIIKFLRKKCSPPSY 1252
             ..||   |..:| :.|.:.:|.:|...::.:..|.|:
plant  1113 -APSY---WITTLFVVLSTMMPYFIFSAIQMRFFPMSH 1146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	21/51 (41%)
		ATPase-Plipid	228..1252	CDD:273734	333/1151 (29%)
		E1-E2_ATPase	323..525	CDD:278548	63/232 (27%)
		Cation_ATPase	<704..783	CDD:289987	23/78 (29%)
		HAD_like	<975..1019	CDD:304363	24/43 (56%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	56/260 (22%)
AT1G26130	NP_001185096.1	PhoLip_ATPase_N	43..106	CDD:292826	22/66 (33%)
		ATPase-Plipid	59..1150	CDD:273734	334/1153 (29%)
		Cation_ATPase	523..628	CDD:289987	35/136 (26%)
		COG4087	<842..900	CDD:226572	30/57 (53%)
		PhoLip_ATPase_C	893..1144	CDD:292829	56/261 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930