DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31729 and ACA.l

DIOPT Version :9

Sequence 1:	NP_609634.1	Gene:	CG31729 / 34736	FlyBaseID:	FBgn0051729	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_172780.1	Gene:	ACA.l / 837881	AraportID:	AT1G13210	Length:	1203	Species:	Arabidopsis thaliana

Alignment Length:	1137	Identity:	320/1137 - (28%)
Similarity:	529/1137 - (46%)	Gaps:	194/1137 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 NEIRNQKYNFITFLPLVLFEQFRFFLNLYFL------LMALSQFIPDIRIGYPYTYWGPLGFVLM 289
            |.:|:.||...:|:|..||||||...|.|||      |.|||.:       .|.:...||.||:.
plant    58 NYVRSTKYTLASFIPKSLFEQFRRVANFYFLVTGVLSLTALSPY-------SPISALLPLTFVIA 115

  Fly   290 VTICREAVDDLRRHQRDHEVNSQKYKRLSSTNI---SGYEMVPSSKLKVGDVIIVEKNERVPADL 351
            .::.:||::|..|.::|.|:|::|.|......|   .|:.     .||||:::.|||:|..||||
plant   116 ASMVKEAIEDWGRKKQDIEMNNRKVKVHDGNGIFRREGWR-----DLKVGNIVRVEKDEFFPADL 175

  Fly   352 ILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQK-LSRDSELHSIDASFYVEKPQNDIHSFIA 415
            :||.:|......:|.|..|||||:.|.:..:..|.. |..||:...:.|....|.|..|:::|:.
plant   176 LLLSSSYEDSICYVETMNLDGETNLKVKQGLEATSSALHEDSDFKELKAVVKCEDPNADLYTFVG 240

  Fly   416 TFCMADGSEDTGLSVENTLWANTVVA-AGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGL 479
            |....:  :...||:...|..::.:. .....|:|::||.:|:.:.|::.|.||...::.:::.:
plant   241 TLHFEE--QRLPLSITQLLLRDSKLRNTEYIYGVVVFTGHDTKVIQNSTDPPSKRSRIERKMDKI 303

  Fly   480 TKVLFCAVLGLSLVMMMLKGF---------GG---PWY--------------------RYMFRFV 512
            ..::|..|..:|.:..::.|.         ||   .||                    .:.|..|
plant   304 IYLMFGVVFLMSFIGSIVFGIETREDRVRNGGRTERWYLRPDNADIFFDPDRAPMAAVYHFFTAV 368

  Fly   513 LLFSYIIPISLRVNLDMGKAFYSWQMQND------SNIQGTVVRSTTIPEELGRISYVLTDKTGT 571
            :|:||.|||||.|::::.|...|..:.||      .|.:....|::.:.||||.:..:|:|||||
plant   369 MLYSYFIPISLYVSIEIVKVLQSLFINNDILMYYEENDKPAHARTSNLNEELGMVDTILSDKTGT 433

  Fly   572 LTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDS----------- 625
            ||.|.|.|.|..:...::        |:.|.::..::..:..|    ||..||.
plant   434 LTCNSMEFIKCSIAGTAY--------GRGITEVERSMAMRSNG----SSLVGDDLDVVVDQSGPK 486

  Fly   626 -------TKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTK 683
                   .:.:|.||.:::.:.....:..|.||:||...|.:|
plant   487 IKGFNFLDERVMKGNWVKQRDAAVLQKFFRLLAVCHTAIPETD---------------------- 529

  Fly   684 SVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQI 748
                 ||.||.    .|:|.||||.|.|....:.|....:|..|.::.:....:....:...|::
plant   530 -----EATGSV----SYEAESPDEAAFVVAAREFGFEFFSRTQNGISFRELDLASGKTVERVYRL 585

  Fly   749 LQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWLSEES-----GNMAREGLRT 808
            |.:..|.|..|||.:|||: :.|::....||||.||...:..|....||.     ...|..||||
plant   586 LNVLEFNSARKRMSVIVRD-EDGRLLLLSKGADNVMFERLAKNGRKFEEKTREHVNEYADAGLRT 649

  Fly   809 LVVAKKVLTEEQYSDFETRYNAARLSIT-DRVAKVAAVTESLERELELLCLTGVEDRLQENVRPT 872
            |::|.:.:.|.:|.:|...:|.|:.|:| ||.:.:..:||.:||:|.||..|.|||:||..|...
plant   650 LILAYREVDENEYIEFSKNFNEAKNSVTADRESLIDEITEQMERDLILLGATAVEDKLQNGVPDC 714

  Fly   873 LELLRNAGVRVWMLTGDKLETACCIA----------------------KSSQLIGRNQGL-HVLR 914
            ::.|..||:::|:|||||:|||..|.                      |:.:..|....: |..|
plant   715 IDKLAQAGIKIWVLTGDKMETAINIGFACSLLRQEMKQIIINLETPHIKALEKAGEKDAIEHASR 779

  Fly   915 -SVKTRTDAHQEL----NSFRRKQGHALVISGESLEVCLQ-YYRPEFLELATASPAVVCCRCSPT 973
             ||..:.:..:.|    :|....:..||:|.|:||...|: .::.:||:|||...:|:|||.||.
plant   780 ESVVNQMEEGKALLTASSSASSHEAFALIIDGKSLTYALEDDFKKKFLDLATGCASVICCRSSPK 844

  Fly   974 QKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLL 1038
            |||.|..|::..|||.|.|:|||.|||.|:|:||.||||.|.||.||.::.|.:|.||.::.:||
plant   845 QKALVTRLVKSGTGKTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLL 909

  Fly  1039 LIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL- 1102
            |:||...|.|.:::..:..::.:.......::.|....|:...|..:.:..::..::..||.:|
plant   910 LVHGHWCYSRISSMICYFFYKNITFGVTVFLYEAYTSFSAQPAYNDWFLSLFNVFFSSLPVIALG 974

  Fly  1103 VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYGALILFVDEFIHIVAIS 1167
            |.|||:::.....:|.||::..:....|:|....|:...::.       ||.:|
plant   975 VFDQDVSARYCYKFPLLYQEGVQNLLFSWKRIIGWMFNGVFT-------ALAIF----------- 1021

  Fly  1168 FSALIMTELIMVAL---TVRTWHRLMVLAELFSLALYLISL--AVLHEYFDW---EFIWSYDFLW 1224
               .:..|.:...|   ..:|..|.::...:::..:::::|  |:...||.|   ..||.....|
plant  1022 ---FLCKESLKHQLYNPNGKTAGREILGGTMYTCVVWVVNLQMALAISYFTWLQHIVIWGSVAFW 1083

  Fly  1225 KVSLITLVSCLPLYIIK----FLRKKCSPPSY 1252
            .:.|:...:..|.:...    |:......|||
plant  1084 YIFLMIYGAITPSFSTDAYKVFIEALAPAPSY 1115

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	21/53 (40%)
		ATPase-Plipid	228..1252	CDD:273734	318/1135 (28%)
		E1-E2_ATPase	323..525	CDD:278548	64/235 (27%)
		Cation_ATPase	<704..783	CDD:289987	24/78 (31%)
		HAD_like	<975..1019	CDD:304363	26/43 (60%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	45/240 (19%)
ACA.l	NP_172780.1	ATPase-Plipid	55..1149	CDD:273734	320/1137 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930