DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31729 and ALA1

DIOPT Version :9

Sequence 1:	NP_609634.1	Gene:	CG31729 / 34736	FlyBaseID:	FBgn0051729	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_568146.1	Gene:	ALA1 / 830375	AraportID:	AT5G04930	Length:	1158	Species:	Arabidopsis thaliana

Alignment Length:	1220	Identity:	339/1220 - (27%)
Similarity:	556/1220 - (45%)	Gaps:	246/1220 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 SVAASGGSAAT-GDL-SNGATHSTTVIDPENGSSTVFYQHNRRKSKSRSIGNVCKLCLCSCWRKW 207
            ||::......| ||| |....|.:...|.|                           :.|..:|.
plant    24 SVSSKDNKEVTFGDLGSKRIRHGSAGADSE---------------------------MLSMSQKE 61

  Fly   208 FRPRELRARTVN-LGRVNTE-KFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIP 270
            .:..:.|...:| ..|.|.. :|..|.|:..||:..||||..|||||.....:|||::|:...:|
plant    62 IKDEDARLIYINDPDRTNERFEFTGNSIKTAKYSVFTFLPRNLFEQFHRVAYIYFLVIAVLNQLP 126

  Fly   271 DIRIGYPYTYWG------PLGFVLMVTICREAVDDLRRHQ-------------RDHEVNSQKYKR 316
            .:.:      :|      ||.|||:|:..::|.:|.|||:             .||:...:|:|.
plant   127 QLAV------FGRGASIMPLAFVLLVSAIKDAYEDFRRHRSDRVENNRLALVFEDHQFREKKWKH 185

  Fly   317 LSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLA 381
                            ::||:||.|:.|:.:|.|::||.|||.:|.|:|:|..||||::.|.|.|
plant   186 ----------------IRVGEVIKVQSNQTLPCDMVLLATSDPTGVVYVQTTNLDGESNLKTRYA 234

  Fly   382 VPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSEDT---------GLSVENTLWAN 437
            ...|  |.:.:::.|.:.....|||..:|:.|.|.. ..||...:         |..::||.|
plant   235 KQET--LLKAADMESFNGFIKCEKPNRNIYGFQANM-EIDGRRLSLGPSNIILRGCELKNTAW-- 294

  Fly   438 TVVAAGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEIN------GLTKVLFCAVLGL------ 490
                   |.|:|:|.|.||::::|||...||...|:..:|      .|..::.|.:...
plant   295 -------ALGVVVYAGGETKAMLNNSGAPSKRSRLETRMNLEIILLSLFLIVLCTIAAATAAVWL 352

  Fly   491 --------SLVMMMLKGF----GGPWYRY----------MFRFVLLFSYIIPISLRVNLDM---G 530
                    :::....|.:    ||..|:|          .|..|:::..:|||||.:::::   |
plant   353 RTHRDDLDTILFYRRKDYSERPGGKNYKYYGWGWEIFFTFFMAVIVYQIMIPISLYISMELVRIG 417

  Fly   531 KAFYSW---QMQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHD-- 590
            :|::..   ||.::|:......|:..|.|:||:|.|:.:|||||||.|:|.|:...:..|.:.
plant   418 QAYFMTNDDQMYDESSDSSFQCRALNINEDLGQIKYLFSDKTGTLTDNKMEFQCACIEGVDYSDR 482

  Fly   591 --ADTFHHIGQMIQKLSGNILQQQ-----QGSLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVR 648
              ||: .|.|..|: :.|.||:.:     ...|...:..|.:|:           |..|..|...
plant   483 EPADS-EHPGYSIE-VDGIILKPKMRVRVDPVLLQLTKTGKATE-----------EAKRANEFFL 534

  Fly   649 ALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKW 713
            :||.|:.:.|:        ||..|       .|...:::            ||..||||.|||..
plant   535 SLAACNTIVPI--------VSNTS-------DPNVKLVD------------YQGESPDEQALVYA 572

  Fly   714 TEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTG----QIT 774
            ....|..||.|....:.:.|:..::      .:.:|.|..|.|:.|||.:|:     |    .:.
plant   573 AAAYGFLLIERTSGHIVINVRGETQ------RFNVLGLHEFDSDRKRMSVIL-----GCPDMSVK 626

  Fly   775 FYLKGADVVMSSIVQYNDWLSEESGNMARE-----------GLRTLVVAKKVLTEEQYSDFETRY 828
            .::||||..|..:      :.|..|.:..|           |||||||..:.|.:.::..:.:.:
plant   627 LFVKGADSSMFGV------MDESYGGVIHETKIQLHAYSSDGLRTLVVGMRELNDSEFEQWHSSF 685

  Fly   829 NAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLET 893
            .||..::..|...:..|..::|..|.::..|.:||:||..|...:|.||.||::||:|||||.||
plant   686 EAASTALIGRAGLLRKVAGNIETNLRIVGATAIEDKLQRGVPEAIESLRIAGIKVWVLTGDKQET 750

  Fly   894 ACCIAKSSQLIGRNQGLHVLRS------VKTRTDAHQELNSFRRKQGHALVISGESLEVCLQYYR 952
            |..|..||:|:.||....|:.|      .::..:|:..:.|.......||:|.|.||...|....
plant   751 AISIGFSSRLLTRNMRQIVINSNSLDSCRRSLEEANASIASNDESDNVALIIDGTSLIYVLDNDL 815

  Fly   953 PEFL-ELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGRE 1016
            .:.| ::|....|::|||.:|.|||.:|||::..|...|.|:|||.|||||||.||.||||.|:|
plant   816 EDVLFQVACKCSAILCCRVAPFQKAGIVALVKNRTSDMTLAIGDGANDVSMIQMADVGVGISGQE 880

  Fly  1017 GRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTL---QAVFSAVFYLSS 1078
            ||||.:|.||::.||..:..|||:||..:|:|...:..:..:|..:...:   ..:|:.....::
plant   881 GRQAVMASDFAMGQFRFLVPLLLVHGHWNYQRMGYMILYNFYRNAVFVLILFWYVLFTCYTLTTA 945

  Fly  1079 VALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKG-RSLSYKTFFIW--VL 1139
            :..:...|   ||.:||..|...: :||:|:..:|.:.:|:||   ..| |:..|.|...|  ::
plant   946 ITEWSSVL---YSVIYTAIPTIIIGILDKDLGRQTLLDHPQLY---GVGQRAEGYSTTLFWYTMI 1004

  Fly  1140 ISIYQGGVIMYGALILFVDEFIHIVAI----SFSALIMTELIMVALTVRTWHRLMVLAELFSLAL 1200
            .:|:|...|.:..:..:....|...::    :.:|:::..| .:|:.|..|:.:...|...|:..
plant  1005 DTIWQSAAIFFIPMFAYWGSTIDTSSLGDLWTIAAVVVVNL-HLAMDVIRWNWITHAAIWGSIVA 1068

  Fly  1201 YLISLAVLHEYFDWEFIW-------SYDFLWKVSLITLVSCLPLYIIKFL 1243
            ..|.:.|:.........|       ::.|.:.:..|.:.|.||.:.||||
plant  1069 ACICVIVIDVIPTLPGYWAIFQVGKTWMFWFCLLAIVVTSLLPRFAIKFL 1118

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	19/51 (37%)
		ATPase-Plipid	228..1252	CDD:273734	323/1133 (29%)
		E1-E2_ATPase	323..525	CDD:278548	67/244 (27%)
		Cation_ATPase	<704..783	CDD:289987	25/82 (30%)
		HAD_like	<975..1019	CDD:304363	27/43 (63%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	55/241 (23%)
ALA1	NP_568146.1	PLN03190	1..1158	CDD:215623	339/1220 (28%)
		PhoLip_ATPase_N	70..133	CDD:292826	22/68 (32%)
		Cation_ATPase	539..638	CDD:289987	34/136 (25%)
		HAD_like	<854..885	CDD:304363	23/30 (77%)
		PhoLip_ATPase_C	885..1125	CDD:292829	55/241 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930