Protein Alignment CG31729 and Atp8a2

DIOPT Version :9

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_038949921.1
• Gene: Atp8a2 / 691889
• RGDID: 1594597
• Length: 1200
• Species: Rattus norvegicus
• Alignment Length: 1160
• Identity: 327/1160 - (28%)
• Similarity: 532/1160 - (45%)
• Gaps: 193/1160 - (16%)

  Fly   175 SSTVFYQHNRRKSKSRSIGNVCKLCLCSCWRKWFRPRELRARTVNLGRVNTEKFPPNEIRNQKYN 239
            ||..:.:.....|::.|:|:               ..|..||.:.|.:.:..||..|.|...||:
  Rat    30 SSAGYKKAEDEMSRATSVGD---------------QLEAPARIIYLNQSHLNKFCDNRISTAKYS 79

  Fly   240 FITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQ 304
            .:||||..|:||.|...|.:||.:||.|.|||:.....||...||..:|.:...:|.|:|.:||:
  Rat    80 VLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIVEDFKRHK 144

  Fly   305 RDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQ 369
            .|:.||.:|...|.:   ..:..:...::.|||::.|...:.:|||::|..:|:..|..:|.|..
  Rat   145 ADNAVNKKKTIVLRN---GMWHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETAN 206

  Fly   370 LDGETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSEDT-------- 426
            |||||:.|.|..:.:|..:.....|..:......|.|...::.|..|..: ||....
  Rat   207 LDGETNLKIRQGLSHTADMQTREVLMKLSGRIECEGPNRHLYDFTGTLHL-DGKSSVALGPDQIL 270

  Fly   427 --GLSVENTLWANTVVAAGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLG 489
              |..:.||.|         ..|:|:|||.:|: :|.||   :|..|....:..:|.|....:.|
  Rat   271 LRGTQLRNTQW---------VFGVVVYTGHDTK-LMQNS---TKAPLKRSNVEKVTNVQILVLFG 322

  Fly   490 LSLVMMMLKGFGG----------PWY------------RYMFRFVLLFSYIIPISLRVNLDMGK- 531
            :.|||.::...|.          .||            ..:..|::|::.:|||||.|.|::.|
  Rat   323 ILLVMALVSSVGALFWNGSHGGKSWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKY 387

  Fly   532 ---AFYSWQ-----MQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVS 588
               .|.:|.     ::||:   ..:.|::.:.||||::.|:.:|||||||.|.|.|||..:..|
  Rat   388 TQALFINWDTDMYYIENDT---PAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGV- 448

  Fly   589 HDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKPMMFGN-RMRRPEGWREWEAVRALAL 652
                |:.|..::.::.|.:...:.   .|..|...|...|.:..| ....|......|.:..||:
  Rat   449 ----TYGHFPELAREQSSDDFCRM---TSCPSDSCDFNDPRLLKNIEDEHPTAPCIQEFLTLLAV 506

  Fly   653 CHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASP------------ 705
            ||.|.|..|.::                    :|             |||:||
  Rat   507 CHTVVPEKDGDE--------------------II-------------YQASSPGVNLCGVGSLLA 538

  Fly   706 DEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKT 770
            ||.||||..:::|.....|...::.::.....:.      :.||.:..|:|:.|||.:||| ..:
  Rat   539 DEAALVKGAKKLGFVFTGRTPYSVIIEAMGQEQT------FGILNVLEFSSDRKRMSVIVR-MPS 596

  Fly   771 GQITFYLKGAD-VVMSSIVQYNDWLSEESGNM---AREGLRTLVVAKKVLTEEQYSDFETRYNAA 831
            ||:..|.|||| |:...:.:.:.::.|...::   |.||||||.||...|:|.:|.::...|..|
  Rat   597 GQLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEA 661

  Fly   832 RLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACC 896
            .:.:.||..::....|.:|:.|.||..|.:|||||..|..|:..|..|.:::|:|||||.|||..
  Rat   662 SIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAIN 726

  Fly   897 IAKSSQLIGRNQGLHVLRSVK---TRTDAHQEL----NSFRRKQGHALVISGESLEVCLQY-YRP 953
            |..|.:|:.:|..|.:|:...   ||....|..    |...::...||:|.|.:|:..|.: .|.
  Rat   727 IGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRR 791

  Fly   954 EFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGR 1018
            .||:||.:..||:|||.||.||:::|.:::|.....|.|:|||.|||.|||.|..||||.|.||.
  Rat   792 SFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGM 856

  Fly  1019 QASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQ 1083
            ||:...|::|.|||::.||||:||..||.|......:..::.:::..::..|:.|...|...|::
  Rat   857 QATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFE 921

  Fly  1084 GFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGV 1147
            .:.:..|:.::|..|.|:| :.::..|.|:.:.:|:|||........:.|.|  |       |..
  Rat   922 RWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNAEGFNTKVF--W-------GHC 977

  Fly  1148 I--MYGALILF-----------------VDEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLA 1193
            |  :..:||||                 ..:::.:..|.::.:::|..:...|....|.:...||
  Rat   978 INALVHSLILFWVPMKALEHDTPLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLA 1042

  Fly  1194 ELFSLALYLISLAVLHEYFDW-------------EFIWSYDFLWKVSLITLVSCL 1235
            ...|:.::|:...|...:  |             ..:.|....|...|:...:||
  Rat  1043 VWGSMLIWLVFFGVYSTF--WPTIPIAPDMKGQATMVLSSAHFWLGLLLVPTACL 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	23/51 (45%)
		ATPase-Plipid	228..1252	CDD:273734	317/1107 (29%)
		E1-E2_ATPase	323..525	CDD:278548	58/233 (25%)
		Cation_ATPase	<704..783	CDD:289987	27/91 (30%)
		HAD_like	<975..1019	CDD:304363	22/43 (51%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	53/248 (21%)
Atp8a2	XP_038949921.1	ATPase-Plipid	68..1118	CDD:273734	317/1107 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860