Protein Alignment CG31729 and atp8b1

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001025562.1
• Gene: atp8b1 / 594952
• XenbaseID: XB-GENE-490143
• Length: 1250
• Species: Xenopus tropicalis
• Alignment Length: 1222
• Identity: 346/1222 - (28%)
• Similarity: 567/1222 - (46%)
• Gaps: 232/1222 - (18%)

  Fly   170 DPENGSSTVFYQHNRRKSKSRSIGNVCKLCLCSCW------RKWFRPRELRARTVNLGRVNTEKF 228
            :||        |:.|.....:|...|.|.|   .|      |.::...|.:.:....  :...|:
 Frog    39 EPE--------QNRRNVQAEQSREPVIKEC---TWQVKANDRNFYDQPEFKKKVFLC--LKKSKY 90

  Fly   229 PPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTIC 293
            ..|.|:..|||.|||||:.|:|||:...|.|||::.:.|.||.|......|...||..||.:|..
 Frog    91 AGNAIKTYKYNPITFLPVNLYEQFKRAANAYFLVLLILQTIPQISTVTWSTTLIPLLLVLGITAI 155

  Fly   294 REAVDDLRRHQRDHEVNSQKYKRLSSTNISG-YEMVPSSKLKVGDVIIVEKNERVPADLILLRTS 357
            ::.|||:.||:.|:|:|:    |.|.....| ::......:.|||:|.:.|||.||||::||.:|
 Frog   156 KDLVDDIARHKMDNEINN----RPSEVITDGRFKKTKWKHIHVGDIIRINKNEFVPADVLLLSSS 216

  Fly   358 DRSGSVFVRTDQLDGETDWKPRLAVPYTQK-LSRDSELHSIDASFYVEKPQNDIHSFIATFCM-- 419
            |.:...:|.|.:|||||:.|.::::..|.| |.::.:|...|.....|:|.|.:..|:.|...
 Frog   217 DPNSLCYVETAELDGETNLKFKMSLEITDKLLQKEEQLAGFDGLVECEEPNNRLDKFVGTLFWRG 281

  Fly   420 ------ADGSEDTGLSVENTLWANTVVAAGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEING 478
                  ||.....|.:|.||.:.:         |:|::.|.:|:.:.|:.:.|.|...:|..:|.
 Frog   282 NSFGLDADKILLRGCTVRNTEYCH---------GLVLFAGADTKIMRNSGKTRLKRTKIDYLMNY 337

  Fly   479 LTKVLF----CAVLGLSLVMMMLKGFGG----PWYRY--------------MFRFVLLFSYIIPI 521
            :...:|    .|..||::.....:...|    .||.|              .:.::::.:.::||
 Frog   338 MVYTIFVLLILAAAGLAIGQTFWEAKLGAANVSWYLYDGNNYSPSYRGFLAFWGYIIVLNTMVPI 402

  Fly   522 SLRVNLD---MGKAFY-SWQMQNDSNIQGT--VVRSTTIPEELGRISYVLTDKTGTLTQNEMVFK 580
            ||.|:::   :|:::: :|.:|...:.:.|  ..|:||:.|:||:|.|:.:|||||||||.|.||
 Frog   403 SLYVSVEVIRLGQSYFINWDLQMYFSPKDTPAKARTTTLNEQLGQIQYIFSDKTGTLTQNIMTFK 467

  Fly   581 KIHL-GIVSHDADTFHHIGQMIQ-KLSGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWRE 643
            |..: |....|.|.....||..| ..|.|.|.....:...:          ....::|..:....
 Frog   468 KCTINGTTYGDDDDELKSGQTKQVDFSWNPLADPSFTFHDN----------YLIEQIRAGKDKDV 522

  Fly   644 WEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEI 708
            :|..:.|||||.|                                 ....||.|..||||||||.
 Frog   523 YEFFKLLALCHTV---------------------------------MAEKTDGELIYQAASPDEG 554

  Fly   709 ALVKWTEQVGLTLIARDLNTMTL----QVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESK 769
            |||......|...::|..:|:|:    |.||          |::|.:..|.|:.|||.||||: .
 Frog   555 ALVTAARNFGFVFLSRTQSTITISELGQEKT----------YEVLAILDFNSDRKRMSIIVRQ-P 608

  Fly   770 TGQITFYLKGADVVMSSIVQYNDWLSEESGN----MAREGLRTLVVAKKVLTEEQYSDFETRYNA 830
            .|:|..|.||||.|:...:..::.:.:::..    .|...||||.:..|.:.:..:.::..:|..
 Frog   609 DGRIRLYCKGADTVIYERLHPDNPIKDQTQKALDIFANASLRTLCLCYKDINKGDFENWSKKYKQ 673

  Fly   831 ARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETAC 895
            |.::.::|...:..|.|::|.:|:||..|.:||:||::|..|:..|..|.:::|:|||||.|||.
 Frog   674 ASVATSNRDEALDRVYEAIETDLKLLGATAIEDKLQDDVSGTIFNLARADIKIWVLTGDKKETAE 738

  Fly   896 CIAKSSQLI--------GRNQGLHVLRSVKTRTDAHQELNSFRRKQG---------------HAL 937
            .|..|.:|:        |.:..:|:      :|....:.|.....||               |||
 Frog   739 NIGYSCKLLDDDTEILYGEDINVHL------QTRMENQRNQMSGNQGAQSNQSGAFLPTDKKHAL 797

  Fly   938 VISGESL-EVCLQ------------------------------YYRPE-----FLELATASPAVV 966
            :|:|..| |:.|:                              |...|     |::||....||:
 Frog   798 IITGSWLNEILLEKKKRKKKRLKLKFPRTKEEKEQQLHEKLKAYALKEQRQRSFVDLACECSAVI 862

  Fly   967 CCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQF 1031
            |||.:|.|||.||.|::::....|.|:|||.|||:||:.|..||||.|:||.||.::.|:|..||
 Frog   863 CCRVTPKQKAMVVDLVKRYKKAVTLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQF 927

  Fly  1032 SHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTM 1096
            .::.:|||:|||.||.|.....::..::....|.:...:|.....|:..:|:.:.:..|:.||:.
 Frog   928 RYLQRLLLVHGRWSYIRMCKFLRYFFYKNFSFTLVHFWYSFFNGFSAQTVYEDWFITLYNVLYSS 992

  Fly  1097 FPVFSL-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGV-------IMYGAL 1153
            .||..: :||||::.:.::.:|.||....|....:||.||    :|::.|.|       |.|||.
 Frog   993 LPVLLVGLLDQDVSDKLSLAFPRLYVPGQKDLLFNYKKFF----LSLFHGIVTSLIIFFIPYGAF 1053

  Fly  1154 ILFV-------DEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYL-----ISLA 1206
            :|.:       .::......:.:||::|....:.|....|..:...:...|:|:|.     :..|
 Frog  1054 LLTMGQDGEAPSDYQSFAVTTATALVITVNFQIGLDTSYWTFVNAFSIFGSIAIYFGIMFDLHSA 1118

  Fly  1207 VLHEYFDWEFIWS--------YDFLWKVSLITLVSC-LPLYIIKFLRKKCSP 1249
            .:|..|...||::        ..:||...::|:..| ||:..::||.|...|
 Frog  1119 GIHVLFPSMFIFTGAAPNALRQPYLWLTIILTVAFCLLPIVALRFLAKTIWP 1170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	314/1068 (29%)
		Cation_ATPase	<704..781	CDD:463817	30/80 (38%)
atp8b1	NP_001025562.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		4/20 (20%)
		P-type_ATPase_APLT_Dnf-like	92..1049	CDD:319770	306/1033 (30%)