Protein Alignment CG31729 and atp8b4

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_687715.4
• Gene: atp8b4 / 559291
• ZFINID: ZDB-GENE-121116-7
• Length: 1214
• Species: Danio rerio
• Alignment Length: 1161
• Identity: 337/1161 - (29%)
• Similarity: 539/1161 - (46%)
• Gaps: 184/1161 - (15%)

  Fly   204 WRKWFRPRELRARTVNLGRVNTEKF--PPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALS 266
            |:|.....|.|....| .|...|:|  ..|.|:..|||..||||:.|||||:.|.|.|||::.:.
Zfish    23 WKKDVHIEEERHVRAN-DRDYNERFSYADNRIKTAKYNVFTFLPINLFEQFQRFANAYFLVLLIL 86

  Fly   267 QFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSS 331
            |.||:|.....:|...||..||.:|..::|.||..||:.|.:||:::.:.|....:...:.:
Zfish    87 QLIPEISSLSWFTTIVPLVLVLAITAVKDATDDYFRHKSDQQVNTRQSQVLIKGKLQNEKWM--- 148

  Fly   332 KLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRD-SELH 395
            .::|||||.:|.|:.|.|||:||.:|:..|..::.|.:|||||:.|.|.|:..|..|..| ::|.
Zfish   149 NVRVGDVIKLENNQFVAADLLLLSSSEPYGLCYIETAELDGETNLKVRQALTVTSDLGDDVAKLA 213

  Fly   396 SIDASFYVEKPQNDIHSFIATFCMADGSED--------TGLSVENTLWANTVVAAGTATGIVIYT 452
            ..:.....|.|.|.:..||.|....|....        .|..:.||.|         ..|:||:.
Zfish   214 DFNGEVICEPPNNKLDKFIGTLYWKDNKYPLDNEKMLLRGCVLRNTEW---------CFGLVIFA 269

  Fly   453 GCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVM-----MMLKGFGGPWYRYM---- 508
            |.:|:.:.|..:.:.|...:|..:|.|...:|..::.:.:::     :..:..|..::.|:
Zfish   270 GLQTKLMQNCGRTKFKRTSIDKLMNTLVLWIFGFLICMGIILAIGNTIWEQSVGSDFWAYLQWKE 334

  Fly   509 -------------FRFVLLFSYIIPISLRVNLD---MGKAFY-SW--QMQNDSNIQGTVVRSTTI 554
                         :.::::.:.::||||.|:::   :|.::: :|  :|...........|:||:
Zfish   335 LTVNAVFSGFLTFWSYIIILNTVVPISLYVSVEVLRLGHSYFINWDRRMYYSRKDTPAEARTTTL 399

  Fly   555 PEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQ--------KLSGNILQQ 611
            .||||::.::.:|||||||||.|||.|..:...:: .|.|...|..:.        ..|.|.|..
Zfish   400 NEELGQVEFIFSDKTGTLTQNIMVFNKCSINGKTY-GDVFDEFGHKVDITEKTPCVDFSFNPLMD 463

  Fly   612 QQGSLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTG 676
            ::.....||        ::...::..|   ...|..|.|||||.|.|   :|.|
Zfish   464 RKFRFHDSS--------LVEAIKLEEP---LVQEFFRLLALCHTVMP---EERN----------- 503

  Fly   677 GNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTL----QVKTPS 737
                              :.|..|||.||||.|||......|....:|...|:||    |..|
Zfish   504 ------------------EGELVYQAQSPDEGALVTAARNFGFVFRSRTPETITLYEMGQAVT-- 548

  Fly   738 EDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVM-SSIVQYNDWL----SEE 797
                    ||:|.:..|.:..|||.:|||..| ||:..|.||||.:: ..:...|:.|    ||.
Zfish   549 --------YQLLAILDFNNVRKRMSVIVRNPK-GQLKLYSKGADTILFDRLDPSNEELMFTTSEH 604

  Fly   798 SGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVE 862
            ....|.||||||.:|.|.|.|:.:.::..:...|..::.:|..|:.|:.|.:|:.:.||..|.:|
Zfish   605 LNEFAGEGLRTLALAYKDLDEDVFDEWTKKLLFASTALDNREEKLGALYEEIEQGMMLLGATAIE 669

  Fly   863 DRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVKTRTDAHQELN 927
            |:|||.|..|:..|..|.:::|:|||||||||..|..|..::..:.....:.|..|..:..|||.
Zfish   670 DKLQEGVPETIACLTLANIKIWVLTGDKLETAMNIGYSCNMLRDDMNEVFIISGHTMLEVQQELR 734

  Fly   928 SFRRK--------------------------------QGHALVISGESLEVCLQYYRPEFL-ELA 959
            :.:.:                                ..:||:|:|.||...|:....:.| ::|
Zfish   735 TAKERIMGPSKDKFSSGLDMEKTELYSVDSVFEETIIAEYALIINGHSLAHALEAELEQILVDVA 799

  Fly   960 TASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAG 1024
            ....:|:|||.:|.|||.||.||::|....|.|:|||.||||||:.|..||||.|:||.||.||.
Zfish   800 CLCKSVICCRVTPLQKALVVELIKRHKRAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLAS 864

  Fly  1025 DFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVG 1089
            |:|..||.::.:|||:|||.||.|......:..::....|.:...:..:...|:..:|..:.:..
Zfish   865 DYSFAQFRYLQRLLLVHGRWSYHRMCNFLCYFFYKNFAFTLVHFWYGFLCGFSAQTVYDQWFITL 929

  Fly  1090 YSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGV---IMY 1150
            ::.:||..||.:: :.|||:..:.::.||.||:.....:..:.:.||...|..:|...:   |.|
Zfish   930 FNIVYTSLPVLAMGLFDQDVNEQYSLRYPNLYRPGQLNQLFNKRKFFTCTLQGVYTSFILFFIPY 994

  Fly  1151 GALILFV--------DEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAV 1207
            ||.:..|        |:....|.|:.|.:|:.. :.:.|....|..:.......|||:|...|..
Zfish   995 GAFMPAVRDDGAQISDQQAFAVTIATSLVIVVS-VQIGLDTNYWTAVNHFFIWGSLAVYFAILFA 1058

  Fly  1208 LHE-----YF--DWEFIWS------YDFLWKVSLITLVSC-LPLYIIKFLRKKCSP 1249
            ::.     .|  .:.||.|      ...:|.|.|:..|.| :|:..::|::....|
Zfish  1059 MNSNGIFTIFPNQFPFIGSARNSLNQKIVWLVILLNTVVCIMPMLAVRFIKTDLYP 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	310/1045 (30%)
		Cation_ATPase	<704..781	CDD:463817	30/80 (38%)
atp8b4	XP_687715.4	P-type_ATPase_APLT_Dnf-like	50..993	CDD:319770	300/1009 (30%)