Protein Alignment CG31729 and Atp8b1

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001001488.2
• Gene: Atp8b1 / 54670
• MGIID: 1859665
• Length: 1251
• Species: Mus musculus
• Alignment Length: 1210
• Identity: 338/1210 - (27%)
• Similarity: 560/1210 - (46%)
• Gaps: 215/1210 - (17%)

  Fly   172 ENGSSTVFYQHNR----RKSKSRSIGNVCKLCLCSCWRKWFRPRELRAR----TVNLGRVNTEKF 228
            |:..|||..:.||    .:.|..:....|      .|:.....|:...:    ......:...|:
Mouse    34 EDQGSTVEPEQNRVNREAEKKRETFRKDC------TWQVKANDRKFHEQPHFMNTKFFCIKESKY 92

  Fly   229 PPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTIC 293
            ..|.|:..|||..||||:.|||||:...|.|||::.:.|.||.|.....||...||..||.:|..
Mouse    93 ASNAIKTYKYNGFTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAI 157

  Fly   294 REAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSD 358
            ::.|||:.||:.|.|:|::..:.:..   ..::::....::|||||.::||:.:|||::||.:|:
Mouse   158 KDLVDDVARHKMDKEINNRTCEVIKD---GRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSE 219

  Fly   359 RSGSVFVRTDQLDGETDWKPRLAVPYT-QKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADG 422
            .:...:|.|.:|||||:.|.::|:..| |.|..:..|.:.|.....|:|.|.:..|..|....
Mouse   220 PNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWK-- 282

  Fly   423 SEDTGLSVENTLWANTVVA-AGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCA 486
            ::...|..:..|....|:. .....|:||:.|.:|:.:.|:.:.|.|...:|..:|.:...:|..
Mouse   283 NQSFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFIV 347

  Fly   487 VL----GLSLVMMMLKGFGG--PWYRY--------------MFRFVLLFSYIIPISLRVNLD--- 528
            ::    ||::.....:...|  .||.|              .:.::::.:.::||||.|:::
Mouse   348 LILVSAGLAIGHAYWEAQVGNYSWYLYDGENATPSYRGFLNFWGYIIVLNTMVPISLYVSVEVIR 412

  Fly   529 MGKA-FYSWQMQ-----NDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKK--IHLG 585
            :|:: |.:|.:|     .|:..:   .|:||:.|:||:|.|:.:|||||||||.|.|||  |:..
Mouse   413 LGQSHFINWDLQMYYAEKDTPAK---ARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGT 474

  Fly   586 IVSHDADTFHHIGQMIQKL--------SGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWR 642
            |.....|...|....|:.:        .|.:.......:....||             :.||
Mouse   475 IYGDHRDASQHSHSKIELVDFSWNTFADGKLAFYDHYLIEQIQSG-------------KEPE--- 523

  Fly   643 EWEAVR----ALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAA 703
                ||    .|::||.|  :.|..|.:                   ||            ||||
Mouse   524 ----VRQFFFLLSICHTV--MVDRIDGQ-------------------IN------------YQAA 551

  Fly   704 SPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRES 768
            ||||.|||......|...:||..||:|:. :..||..     |.:|.:..|.|:.|||.|||| :
Mouse   552 SPDEGALVNAARNFGFAFLARTQNTITVS-ELGSERT-----YNVLAILDFNSDRKRMSIIVR-T 609

  Fly   769 KTGQITFYLKGADVVMSSIVQYNDWLSEESGN----MAREGLRTLVVAKKVLTEEQYSDFETRYN 829
            ..|.|..|.||||.|:...:...:...:|:.:    .|.|.||||.:..|.:.|::::::..::.
Mouse   610 PEGSIRLYCKGADTVIYERLHRMNPTKQETQDALDIFASETLRTLCLCYKEIEEKEFTEWNNKFM 674

  Fly   830 AARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETA 894
            ||.::.::|...:..|.|.:|::|.||..|.:||:||:.|..|:..|..|.:::|:|||||.|||
Mouse   675 AASVASSNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETA 739

  Fly   895 CCIAKSSQLIGRN----QGLHVLRSVKTRTDAHQELNSFRRK-------------QGHALVISGE 942
            ..|..:.:|:..:    .|..:...:.||.:..:.......|             :..||:|:|.
Mouse   740 ENIGFACELLTEDTTICYGEDINSLLHTRMENQRNRGGVSAKFAPPVYEPFFPPGENRALIITGS 804

  Fly   943 SL-EVCLQ------------YYRPE-----------------------FLELATASPAVVCCRCS 971
            .| |:.|:            :.|.|                       |::||....||:|||.:
Mouse   805 WLNEILLEKKTKRSKILKLKFPRTEEERRMRSQSRRRLEEKKEQRQKNFVDLACECSAVICCRVT 869

  Fly   972 PTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAK 1036
            |.|||.||.|::::....|.|:|||.|||:||:.|..||||.|:||.||.::.|:|..||.::.:
Mouse   870 PKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQR 934

  Fly  1037 LLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFS 1101
            |||:|||.||.|.....::..::....|.:...:|.....|:...|:.:.:..|:.||:..||..
Mouse   935 LLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLL 999

  Fly  1102 L-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMY---GALILFVDE--- 1159
            : :||||::.:.::.:|.||....:....:||.||:.:|..:....|:.:   ||.:..|.:
Mouse  1000 MGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKRFFVSLLHGVLTSMVLFFIPLGAYLQTVGQDGE 1064

  Fly  1160 -------FIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYL-----ISLAVLHEYF 1212
                   |...||   |||::|....:.|....|..:...:...|:|||.     ...|.:|..|
Mouse  1065 APSDYQSFAVTVA---SALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLF 1126

  Fly  1213 DWEFIWS--------YDFLWKVSLITLVSC-LPLYIIKFL 1243
            ...|.::        ..::|...::|:..| ||:..|:||
Mouse  1127 PSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFL 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	309/1062 (29%)
		Cation_ATPase	<704..781	CDD:463817	31/76 (41%)
Atp8b1	NP_001001488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		6/17 (35%)
		P-type_ATPase_APLT_Dnf-like	94..1051	CDD:319770	299/1024 (29%)
		DUF2339	<959..>1171	CDD:431054	50/211 (24%)