Protein Alignment CG31729 and Atp8b2

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001355579.1
• Gene: Atp8b2 / 54667
• MGIID: 1859660
• Length: 1209
• Species: Mus musculus
• Alignment Length: 1172
• Identity: 349/1172 - (29%)
• Similarity: 535/1172 - (45%)
• Gaps: 215/1172 - (18%)

  Fly   207 WFRPRELRARTVNLGRVNTEKF--PPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFI 269
            |....|.|||..:  |...|||  ..|.|:..|||.:||||:.|||||:...|.|||.:.:.|.|
Mouse    27 WGTEEERRARAND--REYNEKFQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLI 89

  Fly   270 PDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISG-YEMVPSSKL 333
            |.|.....:|...||..||.:|..::|.||..||:.|::||:    |.|...|:| .:......:
Mouse    90 PQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNN----RHSQVLINGVLQQEQWMNV 150

  Fly   334 KVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSID 398
            .|||:|.:|.|:.|.|||:||.:|:..|..::.|.:|||||:.|.|.|:|.|.:|...|:|...|
Mouse   151 CVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDVSQLARFD 215

  Fly   399 ASFYVEKPQNDIHSFIATFCMADGSED--------TGLSVENTLWANTVVAAGTATGIVIYTGCE 455
            .....|.|.|.:..|..|....:....        .|..:.||.|         ..|:||:.|.:
Mouse   216 GEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEW---------CFGLVIFAGPD 271

  Fly   456 TRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGG---------------PW- 504
            |:.:.|:.:.:.|...:|..:|  |.||:  :.|..:.|.::...|.               ||
Mouse   272 TKLMQNSGRTKFKRTSIDRLMN--TLVLW--IFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWD 332

  Fly   505 ----------YRYMFRFVLLFSYIIPISLRVNLDMGKAFYSWQMQNDSNI------QGTVVRSTT 553
                      :...:.::::.:.::||||.|::::.:..:|:.:..|..:      .....|:||
Mouse   333 EAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTT 397

  Fly   554 IPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSS 618
            :.||||::.|:.:|||||||||.|||.|..:...|: .|.|..:|...:.
Mouse   398 LNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY-GDVFDVLGHKAEL--------------- 446

  Fly   619 SSSGGDSTKPMMFGNRMRRPEGWREW-----EAV-----------RALALCHNVTPVSDDEDNRS 667
                |:..:|:.|.......:.:..|     |||           |.|:|||.   |..:|.|
Mouse   447 ----GERPEPVDFSFNPLADKKFLFWDSSLLEAVKMGDPHTHEFFRLLSLCHT---VMSEEKN-- 502

  Fly   668 VSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQ 732
                                       :.|..|:|.||||.|||......|....:|...|:|:
Mouse   503 ---------------------------EGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITV- 539

  Fly   733 VKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVM---------SSIV 788
                 .:....:.||:|.:..|.:..|||.:|||..: |:|..|.||||.::         ..:.
Mouse   540 -----HELGTAITYQLLAILDFNNIRKRMSVIVRNPE-GKIRLYCKGADTILLDRLHPPTQELLS 598

  Fly   789 QYNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLEREL 853
            ...|.|:|.:|    :||||||:|.|.|.||.|.::..|...|.|:...|..::|::.|.:|.::
Mouse   599 STTDHLNEYAG----DGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDM 659

  Fly   854 ELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVKT 918
            .||..|.:||:||:.|..|:.||..|.:::|:|||||.|||..|..|.:::..:.....:.:..|
Mouse   660 MLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHT 724

  Fly   919 RTDAHQELNSFRRK--------------QG-----------------HALVISGESLEVCLQY-Y 951
            ..:..:||...|:|              ||                 :||||:|.||...|:. .
Mouse   725 VLEVREELRKARKKMVDSSHAVGNGFTYQGNLSSSKLTSVLEAVAGEYALVINGHSLAHALEADM 789

  Fly   952 RPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGRE 1016
            ..||||.|.|..||:|||.:|.||||||.|::|:....|.|:|||.||||||:.|..||||.|:|
Mouse   790 ELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQE 854

  Fly  1017 GRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVAL 1081
            |.||.||.|:|..||..:.:|||:|||.||.|......:..::....|.:...|......|:..:
Mouse   855 GIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTV 919

  Fly  1082 YQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQG 1145
            |..:.:..|:.:||..||.:: |.|||:..:.::.||:||:........:.:.|||.:...||.
Mouse   920 YDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYT- 983

  Fly  1146 GVIMY--------------GALILFVDEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELF 1196
            .|:|:              |..:.....|...||.|   |::...:.:.|....|..:.......
Mouse   984 SVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATS---LVIVVSVQIGLDTGYWTAINHFFIWG 1045

  Fly  1197 SLALYLISLAVLHE--YFD-----WEFI------WSYDFLW-KVSLITLVSCLPLYIIKFLRKKC 1247
            |||:|...|..:|.  .||     :.|:      .:...:| .::|.|.|..:|:...:|||...
Mouse  1046 SLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSL 1110

  Fly  1248 SP 1249
            .|
Mouse  1111 KP 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	320/1059 (30%)
		Cation_ATPase	<704..781	CDD:463817	26/76 (34%)
Atp8b2	NP_001355579.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	12..36		3/8 (38%)
		P-type_ATPase_APLT_Dnf-like	50..991	CDD:319770	314/1021 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1179..1209