Protein Alignment CG31729 and ATP8A

DIOPT Version :9

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Alignment Length: 1275
• Identity: 343/1275 - (26%)
• Similarity: 571/1275 - (44%)
• Gaps: 238/1275 - (18%)

  Fly    75 NSFGSAAGQIRYRNERSRERA----KHS-----NGSYSSISKLAQLTHTSSGV------AGAGSI 124
            |..||:|.|.|.:...:::|.    :||     |..:.|:..|.  ...|.|:      :.:.|:
  Fly    29 NHLGSSASQRRRQQRIAQQRQDSWFRHSMPPAINRDFESLEHLT--PRASDGLDEQLAASVSHSV 91

  Fly   125 GGGGG----GSGSATGIKVTTGDGSVA--------------------ASGGSAATGDLSNGATHS 165
            ..||.    |....:.|.:.:.:.::.                    ||..::..|.||:....|
  Fly    92 HSGGSVTLCGPPDHSSIHLNSANSNLGFIDSDTPNTPVTPVSGLQPPASVSTSVGGTLSSRRRSS 156

  Fly   166 T------TVIDPENGSSTV-------------FYQHNRRKSK-----SRSIGNVCKLCLCSCWRK 206
            .      :::..::|.|.|             |.:..|.:.:     :.|.|
  Fly   157 NRKDSKGSILSRQSGKSRVSLLAQRGLRMTASFLRRKRTEYEDDEDFTSSAG------------- 208

  Fly   207 WFRPRELRARTVNLGRVNTEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPD 271
             :...:...|.:||......|:..|.|...||:||:|||..||||||.:.|.:|||:|:.|.||:
  Fly   209 -YDADDGERRIINLNGPQPTKYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPE 272

  Fly   272 IRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVG 336
            :.....||...||.|:|.|:..:|.::|::||:.|:|:|.:..:||.|   ..:..|..|:|.||
  Fly   273 VSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDS---GSWCTVRWSELTVG 334

  Fly   337 DVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDASF 401
            |:|.|..|...|||||||.:|:.....|:.|..|||||:.|.|.|:|.|.:|....:|..::...
  Fly   335 DIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRI 399

  Fly   402 YVEKPQNDIHSFIATF------CMADGSEDT---GLSVENTLWANTVVAAGTATGIVIYTGCETR 457
            ..|.|...::.|....      ..|.|::..   |..:.||.|         ..|||:|:|.||:
  Fly   400 ECELPNRHLYEFNGVLRETGKPPAALGNDQVLQRGAILRNTAW---------VFGIVVYSGQETK 455

  Fly   458 SVMNNSQPRSKVGLLDMEINGLTKVLF------CAVLGLSLVMMMLKGFGGPWY----------- 505
            .:.|::....|...:|...|....:||      |.:.||..:....:.....||
  Fly   456 LMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLTDFKTKSL 520

  Fly   506 -RYMFRFVLLFSYIIPISLRVNLDMGKAF------YSWQMQNDSNIQGTVVRSTTIPEELGRISY 563
             ..:..|.:|::.:|||||:|.|::.:..      |..:|.::.:....:.|::.:.||||.:.|
  Fly   521 GYNLLTFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKY 585

  Fly   564 VLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKP 628
            :.:|||||||||.|.|||..:....:.|:......|::|    |||.:.:.|....
  Fly   586 IFSDKTGTLTQNVMEFKKCSIAGYVYTAERTPEESQLVQ----NILGRHETSAVIE--------- 637

  Fly   629 MMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGS 693
                            |.:..|::||.|.|...:..|..
  Fly   638 ----------------EFLELLSVCHTVIPERKENGNMI-------------------------- 660

  Fly   694 TDTEHQYQAASPDEIALVKWTEQVGLTLIAR-----DLNTMTLQVKTPSEDNDILLHYQILQLFP 753
                  |.||||||.|||:..::.|.....|     ::|.:.::.:           |::|.:..
  Fly   661 ------YHAASPDERALVEGAQKFGYIFDTRTPKYVEINALGVRKR-----------YEVLNVLE 708

  Fly   754 FTSESKRMGIIVRESKTGQITFYLKGAD-VVMSSIVQYNDWLSEES----GNMAREGLRTLVVAK 813
            |||..|||.:||| :...:|..:.|||| |:...:........|::    ...|.:|||||.:|.
  Fly   709 FTSSRKRMSLIVR-TPENKIKLFCKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAV 772

  Fly   814 KVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRN 878
            ..:..:.|.::...::.|.:::.:|.:|:......:|..|.||..|.:|||||:.|..|:..|.:
  Fly   773 ADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLD 837

  Fly   879 AGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVK---TRTDAHQELNSFRRKQGH----A 936
            ||:.:|:|||||.|||..|..|.:||..:..:.:|....   ||...|:....|:.....    |
  Fly   838 AGIYIWVLTGDKQETAINIGYSCRLISHSMDIIILNEESLDATREVIHRHYGEFKSSSAKDANVA 902

  Fly   937 LVISGESLEVCLQY-YRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDV 1000
            |||.|.:|:..|.. .|.:|.:|......|:|||.||.|||:||.::.:.|...|.|:|||.|||
  Fly   903 LVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDV 967

  Fly  1001 SMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITT 1065
            :|||:|:.|:||.|.||.||:.|.|:||.||.::.:|||:||..:|.|.:.|..:..::.:.:..
  Fly   968 AMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYV 1032

  Fly  1066 LQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKGRSL 1129
            ::..|:.....|...|::.:.:..|:.|:|..|.|:: :.::..|:||.:.||.|||.....:..
  Fly  1033 IELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLF 1097

  Fly  1130 SYKTFFIWVLISIYQGGVIMYGALILFVDE----------FIHIVAISFSALIMTELIMVALTVR 1184
            :.|.|:||:..::.....:.:..|..:..|          ::.:..:.::.:|:|..:...|...
  Fly  1098 NVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSDGKTSDYLLMGNLVYTYVIVTVCLKAGLITN 1162

  Fly  1185 TWHRLMVLAELFSLALYLISLAVLHEYFDWEFIWSYDFLW 1224
            :|..|..||...|:.|:            :.|:..|..:|
  Fly  1163 SWTWLTHLAIWGSIVLW------------FGFLLIYSHVW 1190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	24/51 (47%)
		ATPase-Plipid	228..1252	CDD:273734	307/1059 (29%)
		E1-E2_ATPase	323..525	CDD:278548	65/228 (29%)
		Cation_ATPase	<704..783	CDD:289987	26/84 (31%)
		HAD_like	<975..1019	CDD:304363	23/43 (53%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	48/215 (22%)
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	26/61 (43%)
		ATPase-Plipid	229..1247	CDD:273734	307/1059 (29%)
		E1-E2_ATPase	286..>371	CDD:278548	34/87 (39%)
		Cation_ATPase	645..741	CDD:289987	35/139 (25%)
		HAD_like	<942..1001	CDD:304363	31/58 (53%)
		PhoLip_ATPase_C	988..1240	CDD:292829	48/215 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D11922at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24092
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950