Protein Alignment CG31729 and atp8b2

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_021322579.1
• Gene: atp8b2 / 323754
• ZFINID: ZDB-GENE-030131-2474
• Length: 1359
• Species: Danio rerio
• Alignment Length: 1208
• Identity: 346/1208 - (28%)
• Similarity: 538/1208 - (44%)
• Gaps: 268/1208 - (22%)

  Fly   211 RELRARTVNLGRVNTEKF--PPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIR 273
            |.:||.    .|...|||  ..|.|...|||.|||||:.|||||:...|.|||.:.:.|.||.|.
Zfish    46 RRVRAN----DREYNEKFQYASNCIMTSKYNIITFLPVNLFEQFQEVANTYFLFLLILQLIPQIS 106

  Fly   274 IGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSK---LKV 335
            ....:|...||..||.:|..::|.||..||:.|::||:    |.|...|.|  ::...|   ::|
Zfish   107 SLSWFTTIVPLVLVLSITAVKDATDDYFRHKSDNQVNN----RQSQVLIGG--ILQKEKWMNVRV 165

  Fly   336 GDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDAS 400
            ||:|.:|.|:.|.|||:||.:|:..|..::.|.:|||||:.|.|.::..|.:|...:.|...|..
Zfish   166 GDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQSLSVTSELGDPNNLAQFDGE 230

  Fly   401 FYVEKPQNDIHSFIATFCMADGSEDTGLSVENTLWANTVVA-AGTATGIVIYTGCETRSVMNNSQ 464
            ...|.|.|.:..|..|....:....  ||.:|.|....|:. ..:..|:||:.|.:|:.:.|:.:
Zfish   231 VVCEPPNNKLDRFCGTLYWRECKYP--LSNQNMLLRGCVLRNTESCYGLVIFAGPDTKLMQNSGR 293

  Fly   465 PRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGG---------------PW---------- 504
            .:.|...:|..:|  |.||:  :.|..:.|.::...|.               ||
Zfish   294 TKFKRTSIDRLMN--TLVLW--IFGFLVCMGVILAIGNAVWEKEVGALFQSFLPWDPPVDNFLFS 354

  Fly   505 -YRYMFRFVLLFSYIIPISLRVNLD---MGKAFY-SWQMQNDSNIQGTV--VRSTTIPEELGRIS 562
             :...:.:|::.:.::||||.|:::   :|.::: :|..:...:...|.  .|:||:.||||::.
Zfish   355 AFLSFWSYVIILNTVVPISLYVSVEVIRLGHSYFINWDRRMFCSRSNTAAEARTTTLNEELGQVE 419

  Fly   563 YVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTK 627
            |:.:|||||||||.|.|.|..:        ..|..|:::     |||..||          ...:
Zfish   420 YIFSDKTGTLTQNIMTFNKCSI--------NGHAYGEVV-----NILAAQQ----------KRVQ 461

  Fly   628 PMMFGNRMRRPEGWRE-------------WEAV-----------RALALCHNVTPVSDDEDNRSV 668
            |:.|.:       |..             .|||           |.|:|||.|  :|:::
Zfish   462 PLDFSS-------WNPLADRGFCFYDQSLLEAVMVGDPAVHEFFRVLSLCHTV--MSEEK----- 512

  Fly   669 STASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQV 733
                                     ::.|..|:|.||||.|||......|....:|...|:|.|
Zfish   513 -------------------------SEGELVYKAQSPDEGALVTAARNFGFVFRSRTPGTITTQ- 551

  Fly   734 KTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVM---------SSIVQ 789
                 :....:.|.:|.:..|.:..|||.:|||..: |:|..|.||||.|:         ..:..
Zfish   552 -----ELGKAVTYTLLAILDFNNIRKRMSVIVRNPE-GRIRLYCKGADTVLLERLHSCNHEVMTI 610

  Fly   790 YNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELE 854
            .:|.|:|    .|.:|||||.||.:.|:|||:.::..|:..|..:...|..::||..|.:|:::.
Zfish   611 TSDHLNE----YAVDGLRTLAVAYRDLSEEQWDEWSERFRGADKATDCREDRLAAAYEEIEQDMM 671

  Fly   855 LLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQ------GLHVL 913
            ||..|.:||:|||.|..|:.:|..|.:::|:|||||.|||..|..|.:::..:.      ..|.:
Zfish   672 LLGATAIEDKLQEGVPETIAILSLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVNGHTV 736

  Fly   914 RSVK--TRTDAHQELNSFRRKQG------------------------------------------ 934
            :||:  .|....:.|.|.|.:.|
Zfish   737 QSVREELRKARERMLESARTRDGGKEAEAQGWSGACAFGNGCGAGAAAAAANWAPDESKCPPAQA 801

  Fly   935 ------------HALVISGESLEVCLQY-YRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHT 986
                        .||:|||.||...|:. ...||||.|.|..||:|||.:|.|||.||.|:::|.
Zfish   802 PPSSLLESISGEFALIISGHSLAHALEADMEREFLETACACRAVICCRVTPLQKALVVELVKRHK 866

  Fly   987 GKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAA 1051
            ...|.|:|||.||||||:.|..||||.|:||.||.||.|:|..||..:.:|||:|||.||.|...
Zfish   867 KAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFRFLQRLLLVHGRWSYLRMCR 931

  Fly  1052 LSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVT 1115
            ...:..::....|.:...|......|:..:|..:.:..|:.:||..||.:: :.|||:..:.::.
Zfish   932 FLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGIFDQDVPEQRSLE 996

  Fly  1116 YPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYGALILFVDEFIHIVAISF------------ 1168
            ||:||:........:.:.||    |.|.||   :|.:::||   ||....:|.
Zfish   997 YPKLYEPGQLNLLFNKREFF----ICIAQG---IYTSVVLF---FIPYSVLSHATQSNGVPLADY 1051

  Fly  1169 --------SALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYF-------DWEFIW 1218
                    :||::...:.:||....|..:.......||..|...|..:|...       .:.|:.
Zfish  1052 QTFAVTTATALVIVVSVQIALDTGYWTAINHFFVWGSLGTYFTILFAMHSSILFSIFPKQFHFLG 1116

  Fly  1219 S------YDFLW-KVSLITLVSCLPLYIIKFLRKKCSP 1249
            |      ...:| .::|.|::...|:...:||:....|
Zfish  1117 SAHNTLGQPVVWLTIALATVICIAPVLAFRFLKLDLKP 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	322/1099 (29%)
		Cation_ATPase	<704..781	CDD:463817	26/76 (34%)
atp8b2	XP_021322579.1	P-type_ATPase_APLT_Dnf-like	63..1033	CDD:319770	318/1064 (30%)