Protein Alignment CG31729 and Atp8b3

DIOPT Version :9

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_234937.3
• Gene: Atp8b3 / 299616
• RGDID: 1307622
• Length: 1340
• Species: Rattus norvegicus
• Alignment Length: 1190
• Identity: 335/1190 - (28%)
• Similarity: 547/1190 - (45%)
• Gaps: 245/1190 - (20%)

  Fly   203 CWRKWFRPRELRARTVNLGRVNTEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQ 267
            |||:                   :|:..|.|...|||..:||||.|:||||...|||||.:.:.|
  Rat    39 CWRQ-------------------KKYKSNAIHTAKYNVFSFLPLNLYEQFRRVSNLYFLFIIILQ 84

  Fly   268 FIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSK 332
            .||:|.....:|.:.||..:||:...|:.|||:.||:.|..:|::..:.|...:....:.   ..
  Rat    85 SIPEISTLPWFTLFAPLVCLLMIRAARDLVDDIGRHRSDRIINNRPCQILKGKSFLWKKW---KN 146

  Fly   333 LKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYT-QKLSRDSELHS 396
            |.||||:.:.|:..|||||:||.:::.|...::.|..:||||:.|.|.|:..| .:|:...::.|
  Rat   147 LCVGDVVCLSKDNIVPADLLLLASTEPSSLCYLETADIDGETNLKFRQALMVTHHELTSPKKMAS 211

  Fly   397 IDASFYVEKPQNDIHSFIATFCMADGSEDTGLSVENTLWANTVVA-AGTATGIVIYTGCETRSVM 460
            .......|:|.:.:|.|:.:  :...|....|.:.|.|.....:. ..|..|:|||.|.:|:.:.
  Rat   212 FQGIVTCEEPNSRMHHFVGS--LEWNSRKYPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMK 274

  Fly   461 NNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVM-----MMLKGFGGPWYRYM------------ 508
            |..:...|...||:.:|.|..::|.:::..|:.:     .|:|.|... :.||
  Rat   275 NCGKIHLKRTKLDLMMNKLVILIFMSLVIASMFLTLGFAFMVKEFKAK-HHYMSSMQGRTDAMDS 338

  Fly   509 ----FRFVLLFSYIIPISLRVNLD---MGKA-FYSWQMQ---NDSNIQGTVVRSTTIPEELGRIS 562
                :.|::|.|.::|:::.:..:   :|.: |.:|.:.   ...:|... .|||::.:.||::.
  Rat   339 FFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLSMYYEPLDIPAK-ARSTSLNDHLGQVQ 402

  Fly   563 YVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTK 627
            |:.:|||||||||.|.|||..:...::|:|..|          |.:.::...|.:..:.|
  Rat   403 YIFSDKTGTLTQNIMTFKKCCINGCTYDSDDEH----------GTLRKRNPYSWNPFADG----- 452

  Fly   628 PMMFGNR-----MRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVIN 687
            .:.|.|:     :|..:.....|..|.||:||.|  :..::||:.:
  Rat   453 KLQFYNKELESLVRGKQDRAVQEFWRLLAICHTV--MVQEKDNQLL------------------- 496

  Fly   688 IEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLF 752
                        ||||||||.|||......|...::|..:|:|| |:...|     ..||:|.:.
  Rat   497 ------------YQAASPDEEALVAAARNFGYVFLSRTQDTITL-VELGEE-----RVYQVLAMM 543

  Fly   753 PFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWL----SEESGNMAREGLRTLVVAK 813
            .|.|..|||.::||..: |.|..|.||||.|:...:.:...:    .|.....|.:.||||.:|.
  Rat   544 DFNSVRKRMSVLVRNPE-GSICLYTKGADTVILERLHHKGVMEATTEEVLAAFAEQTLRTLCLAY 607

  Fly   814 KVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRN 878
            |.:.|:.|.::|..:..|.|.:.:|...:..|...||:.|:||.:|.:||:||:.|..|:..|:.
  Rat   608 KDVAEDAYKEWEPEHQEAALLLQNRAQALHQVYNKLEQNLQLLGVTAIEDKLQDGVPETIRCLKK 672

  Fly   879 AGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVK----TRTDAHQELNSFRRKQGH--AL 937
            ..:::|:|||||.|||..|..:.||:..|..:...:.:|    ...|.::...:|:....|  ||
  Rat   673 GNIKMWVLTGDKPETAVNIGFACQLLSENMSILEDKDIKGLLENYWDENEHQRAFQTMTHHNMAL 737

  Fly   938 VISGESLEVCL-------------------------------------QYYR------------- 952
            ||:||.|:..|                                     |.:|
  Rat   738 VINGEFLDQLLLSLRKEPRALVQNAVVDEATQEPGVSALDFLQARRISQMWRNFGTTMATSQSDA 802

  Fly   953 ------PE------FLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQ 1005
                  ||      |::||:...||:|||.:|.|||.||||::|:....|.|:|||.|||:||:.
  Rat   803 SKTRESPEERRERAFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKT 867

  Fly  1006 ADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVF 1070
            ||.|||:.|:||.||....|:.:.||.::.:|||:|||.||.|.....::..::.:.....|..|
  Rat   868 ADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRICKFLRYFFYKTVASMMAQIWF 932

  Fly  1071 SAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELY----KD-------- 1122
            |.....|:..||:|:.:..::.||:..||..: :.:||:|:|.::..||||    ||
  Rat   933 SLFNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYTAGQKDELFNYSIF 997

  Fly  1123 ---LSKGRSLSYKTFFIWVLISI----------YQGGVIMYGALILFVDEFIHIVAISFSALIMT 1174
               ::.|...|...||:.:|:|.          ||.    :|.|          ||||....|..
  Rat   998 VQAIAHGTITSLINFFVTILVSYDMTKTGSSPDYQS----FGVL----------VAISSLLSITL 1048

  Fly  1175 ELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHE--------------YFDWEFIWSYDFLWK 1225
            |:|:|   |:.|..|.|...:.||:.|:|..::...              :.|:..|.....|..
  Rat  1049 EVILV---VKYWTLLFVGTVVVSLSSYVIFTSLTESLLLFRISPKTFPFLFADYNVIREPSSLLV 1110

  Fly  1226 VSLITLVSCLPLYIIKFLRK 1245
            :.|...::.||:..::.:|:
  Rat  1111 IVLNVTLNTLPMLAVRIIRR 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	24/51 (47%)
		ATPase-Plipid	228..1252	CDD:273734	331/1165 (28%)
		E1-E2_ATPase	323..525	CDD:278548	57/224 (25%)
		Cation_ATPase	<704..783	CDD:289987	31/78 (40%)
		HAD_like	<975..1019	CDD:304363	25/43 (58%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	66/265 (25%)
Atp8b3	XP_234937.3	PhoLip_ATPase_N	20..96	CDD:292826	27/75 (36%)
		ATPase-Plipid	45..1143	CDD:273734	331/1165 (28%)
		Cation_ATPase	483..577	CDD:289987	41/133 (31%)
		COG4087	<839..890	CDD:226572	26/50 (52%)
		PhoLip_ATPase_C	883..1131	CDD:292829	66/265 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.950