Protein Alignment CG31729 and Atp10a

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_033858.2
• Gene: Atp10a / 11982
• MGIID: 1330809
• Length: 1508
• Species: Mus musculus
• Alignment Length: 1321
• Identity: 351/1321 - (26%)
• Similarity: 555/1321 - (42%)
• Gaps: 339/1321 - (25%)

  Fly   207 WFRPR----ELRARTVN------LGRVNT----------------EKFPPNEIRNQKYNFITFLP 245
            |.|||    |.|.|||.      ||..::                :....|.::..||..::|||
Mouse    16 WRRPRRRRWEGRTRTVRSNLLPPLGTEDSTIGAPKGERLLMRGCIQHLADNRLKTTKYTLLSFLP 80

  Fly   246 LVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVN 310
            ..|||||....|:||:.:||..|:|.:....|.....|:.|:|.||..::..:|..||:.|||:|
Mouse    81 KNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEIN 145

  Fly   311 ---SQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDG 372
               ...:.|.....::.|    ..:::|||.:.:..||.:|||::||.:||..|...:.|..|||
Mouse   146 HLGCLVFSREEKKYVNRY----WKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDG 206

  Fly   373 ETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSEDTGLSVENTLWAN 437
            ||:.|.|..|....:|..:....:..:....|||.||:..| ..:.|....|..||..||.|...
Mouse   207 ETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRF-RGYIMHSNGEKAGLHKENLLLRG 270

  Fly   438 -TVVAAGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFG 501
             |:.......|||||.|.||::::|||.||.|...|:.::|  ..||:|.:|.:.:.:....|.
Mouse   271 CTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMN--CDVLWCVLLLVCISLFSAVGH- 332

  Fly   502 GPWYR---------------------------YMFRFVLLFSYIIPISLRVNLDMGKA----FYS 535
            |.|.|                           ..|..:::...:|||||.|::::.|.    |.:
Mouse   333 GLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFIN 397

  Fly   536 -----WQMQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHL-GI-VSHDAD- 592
                 :..:.||.:|   .|:..|.|:||:|.|:.:|||||||:|:|||::..: || .||||:
Mouse   398 QDIELYDEETDSQLQ---CRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANA 459

  Fly   593 ---------------------TFHHIGQ--------MIQKLSGNILQQQQGSLSSSSSGGDSTKP 628
                                 |..|.|.        |..|.......::.||.:.:......:|.
Mouse   460 QRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKH 524

  Fly   629 MMFGNRMRR---------------------------------PEGWREWEAVRALALCHNVTPVS 660
            ..|.:.|.:                                 ||....::...||.:|:.|...|
Mouse   525 TAFSSPMEKDITPDPKLLEKVSECDRFLAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTS 589

  Fly   661 DDEDNRSV-------STASTVTG-----------------GNNSPTKS----------------- 684
            .|:..:.|       |...|:..                 ||.|.:||
Mouse   590 PDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASGCSSIGNLSTSKSSHKSGSAFLPSLSQDSM 654

  Fly   685 VINIE------APG--------------------STDT------------EHQYQAASPDEIALV 711
            ::.:|      ||.                    :||.            |.:|:|.||||.|||
Mouse   655 LLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQREQQEGELRYEAESPDEAALV 719

  Fly   712 KWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFY 776
            .........|:.|..:.:::::.....     |.:::|....|.|..|||.:::|...|.:|..|
Mouse   720 YAARAYNCALVDRLHDQVSVELPHLGR-----LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVY 779

  Fly   777 LKGADVVMSSIV----------QYNDWLSEESGN----MAREGLRTLVVAKKVLTEEQYSDFETR 827
            .||||.|:..::          ::...:..::.|    .|.||||||.:||:||::|:|:.:...
Mouse   780 TKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQS 844

  Fly   828 YNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLE 892
            :..|..|:..|...:......||..|.||..||:||||||.|..|:..||.||:::|:|||||.|
Mouse   845 HIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQE 909

  Fly   893 TACCIAKSSQLIGRNQGLHVLRS-----------------------------------------V 916
            ||..||.:.:|:...:.:..|.:                                         |
Mouse   910 TAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPV 974

  Fly   917 KTRTDAHQELNSFRRKQGHALVISGESLEVCLQ-YYRPEFLELATASPAVVCCRCSPTQKAQVVA 980
            .|.|||         ....:|||.|.||...|: ....:||.||....:|:|||.:|.||:.||.
Mouse   975 STSTDA---------SPSPSLVIDGRSLAYALEKSLEDKFLFLAKQCRSVLCCRSTPLQKSMVVK 1030

  Fly   981 LIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRS 1045
            |::......|.|:|||.|||||||.||.||||.|:||.||.:|.||::|:|.::.:||::||...
Mouse  1031 LVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWC 1095

  Fly  1046 YKRSAALSQFVIHRGLIITTLQAVFSAVFY--LSSVALYQGFLMVGYSTLYTMFP-VFSLVLDQD 1107
            |.|.|.:..:..::..:...|  :|...||  .|:.|:...:.::.::.|::..| :.:.|||:|
Mouse  1096 YSRLANMVLYFFYKNTMFVGL--LFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKD 1158

  Fly  1108 ITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYGALILFVDEFIH-------IVA 1165
            :.::..:..|:|||..........:.|::.::.:.:|..|..:...:.:.|..:.       :.|
Mouse  1159 VPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTA 1223

  Fly  1166 ISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYFDWEFIWSYDFLWKVSLIT 1230
            |:    :.|.|:.:.:..:||..|..||..||..|:                      :.|:||.
Mouse  1224 IA----LFTFLLHLGIETKTWTWLNWLACGFSTFLF----------------------FSVALIY 1262

  Fly  1231 LVSCLPLYIIKFLRKKCSPPS 1251
            ..||          ..|.|||
Mouse  1263 NTSC----------ATCYPPS 1273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	322/1196 (27%)
		Cation_ATPase	<704..781	CDD:463817	22/76 (29%)
Atp10a	NP_033858.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		4/6 (67%)
		P-type_ATPase_APLT_Dnf-like	65..1203	CDD:319770	318/1164 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..705		2/24 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1334..1354
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1407..1436
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1481..1508