Protein Alignment CG31729 and atp11a

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_031752894.1
• Gene: atp11a / 100485769
• XenbaseID: XB-GENE-1010941
• Length: 1193
• Species: Xenopus tropicalis
• Alignment Length: 1155
• Identity: 349/1155 - (30%)
• Similarity: 548/1155 - (47%)
• Gaps: 197/1155 - (17%)

  Fly   216 RTVNLGRVN---------TEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPD 271
            ||:.:|...         .:::|.|.|.:.||.|..|:|..||||||...|.|||::.|.|.|.|
 Frog    24 RTIYVGHKQPPPGTEAYIPQRYPDNRIVSSKYTFWNFVPKNLFEQFRRIANFYFLIIFLVQLIID 88

  Fly   272 IRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQ-----KYKRLSSTNISGYEMVPSS 331
            .... |.|...||.||:.||..::..:|..||:.|:.:|..     ::.:|..|.        |.
 Frog    89 TPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQYSVHVVQHGKLVRTQ--------SR 144

  Fly   332 KLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHS 396
            ||:|||:::|.::|..|.||:.|.:|...|:.||.|..||||:..|...|:..|:....:.|:..
 Frog   145 KLRVGDIVMVREDEAFPCDLVFLSSSREDGTCFVTTASLDGESSHKTYYAINDTKSFHHEEEMEG 209

  Fly   397 IDASFYVEKPQNDIHSFIA---TFCMAD-------GSED---TGLSVENTLWANTVVAAGTATGI 448
            :.|:...|:||.|::.|:.   .:..||       |||:   .|.:::||         ....|:
 Frog   210 LHATIECEQPQPDLYKFVGRINIYNEADEPVARPLGSENLLLRGATLKNT---------EKIFGV 265

  Fly   449 VIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLK-------GFGGPWYR 506
            .||||.||:..:|......|...::..:|....|..|.::..:|:..:||       ....|||.
 Frog   266 AIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYIWQSDSSRDEPWYN 330

  Fly   507 Y-----------------MFRFVLLFSYIIPISLRVNLDM----GKAFYSW--QMQNDSNIQGTV 548
            .                 ...|::||:||||:|:.|.::|    |..|.||  :|.:::..:|.:
 Frog   331 QKTDSERQKNKFLGAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFISWDEEMFDETTGEGPI 395

  Fly   549 VRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQ 613
            |.::.:.||||::.|:.||||||||:|.|.|  :...|..|     .:|..:|  .:|.||....
 Frog   396 VNTSDLNEELGQVEYIFTDKTGTLTENNMEF--VECCIEGH-----VYIPHVI--CNGQILPDCM 451

  Fly   614 G---SLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVT 675
            |   ..||..:||...:.:.|                |||.|||.|.  ..|||:......|:.:
 Frog   452 GIDMIDSSPGAGGKEREELFF----------------RALCLCHTVQ--VKDEDHIDGEKKSSHS 498

  Fly   676 GGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDN 740
            |.::                   .|.::||||:|||:..:::|.|.:....|.|.:    .:.:|
 Frog   499 GRSS-------------------VYISSSPDEVALVEGVQRLGYTFLRVKDNYMEI----CNREN 540

  Fly   741 DILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYN--DWLSEESGNMAR 803
            || ..:::||:..|.|..:||.:||| |.||.|..:.||||..:...|:..  |.:.......|.
 Frog   541 DI-EKFELLQVLTFDSVRRRMSVIVR-SSTGDIYLFCKGADSSIFPRVREGKVDQIRARVERNAV 603

  Fly   804 EGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQEN 868
            ||||||.||.|..::::|.........|:|::.||..|:|...|.:|::|.||..|.|||||||.
 Frog   604 EGLRTLCVAYKKFSQDEYEWANKLLKDAQLALQDREKKLAEAYEQIEQDLILLGATAVEDRLQEK 668

  Fly   869 VRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRN-------------QGLH--------- 911
            ...|:|.|:.||::||:|||||:|||.....:.:|..||             |.||
 Frog   669 AADTIESLQKAGIKVWVLTGDKMETASATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSRT 733

  Fly   912 VLRSVKTRTDAHQELNSFRRK-QGHALVISGESLEVCLQ--------YYRPEFLELATASPAVVC 967
            |||..::.|  ....:.|... |.:.|:|.|.:|.:.::        .||..|||:.....||:|
 Frog   734 VLRHSESLT--RDNFSGFSTDFQDYGLIIDGATLSLIMKPREDGSSTNYREVFLEICRNCSAVLC 796

  Fly   968 CRCSPTQKAQVVALI---QKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIP 1029
            ||.:|.||||:|.||   ::|  ..|.|||||.||||||.:|..|:|:.|:|||||:...|::||
 Frog   797 CRMAPLQKAQIVKLIKSSREH--PITLAVGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIP 859

  Fly  1030 QFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLY 1094
            :|.|:.::|||||...|.|.:.|.|:..::.:.....|.::......|...||....:..|:..:
 Frog   860 KFKHLKRMLLIHGHYYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISF 924

  Fly  1095 TMFPV--FSLVLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYGALILFV 1157
            |..|:  :||: :|.::.:.....|.||:|::|...|.::.|..|..:.::...|..:||..|:.
 Frog   925 TSLPILLYSLI-EQHVSVDVLKRDPTLYRDIAKNALLRWRLFIYWTFLGLFDAAVFFFGAYFLYD 988

  Fly  1158 DEFI----------HIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYF 1212
            :..:          ....:.|:.|:.|....:||....|..:.......||..|:| .::|....
 Frog   989 NATVTSNGQMLGNWTFGTLVFTVLVFTVTFKLALDTHYWTWINHFVIWGSLLFYII-FSLLWGGI 1052

  Fly  1213 DWEFI----WSYDFLWKVS---------LITLVSCLPLYIIKFLRKKCSP 1249
            .|.|:    ..|.|:..:|         |:.:||.||..:.|.:.::..|
 Frog  1053 IWPFLNYQRMYYVFIQMLSSGPAWLGIVLLIIVSLLPDVLRKVICRQLWP 1102

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	325/1045 (31%)
		Cation_ATPase	<704..781	CDD:463817	29/76 (38%)
atp11a	XP_031752894.1	P-type_ATPase_APLT_Dnf-like	47..983	CDD:319770	319/1010 (32%)
		MelB	<891..>1092	CDD:441813	43/202 (21%)