Protein Alignment CG31729 and atp8a2

DIOPT Version :9

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_017209427.1
• Gene: atp8a2 / 100330943
• ZFINID: ZDB-GENE-100209-2
• Length: 1211
• Species: Danio rerio
• Alignment Length: 1193
• Identity: 334/1193 - (27%)
• Similarity: 536/1193 - (44%)
• Gaps: 229/1193 - (19%)

  Fly   183 NRRKSKSRSIG----------------------NVCK----------LCLCSCWRK--------- 206
            |||..|..|.|                      |:|.          .|..:.:||
Zfish     4 NRRSKKIHSEGEQLVLTPLSQDSPLRQDQPLGPNMCSRLADRFEKRPACSATGYRKAEDEMSGTT 68

  Fly   207 -WFRPRELRARTVNLGRVNTEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIP 270
             ...|.:..||||.|.|..|.|:..|.:...||..:||||..|:||.|...|.:||.:||.|.||
Zfish    69 SQADPVDATARTVLLNRAQTTKYCDNHVSTAKYGILTFLPRFLYEQIRRAANAFFLFIALMQQIP 133

  Fly   271 DIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKV 335
            |:.....||...||.|:|.|...:|.::|.:||:.|:.||.:|...|.:   ..::.:...::.|
Zfish   134 DVSPTGRYTTLVPLIFILTVAGIKEIIEDYKRHKADNTVNKKKTTVLRN---GAWQTIIWKQVAV 195

  Fly   336 GDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDAS 400
            ||::.|...:.:|||::::.:|:.....:..|..|||||:.|.|..:..|.......:|.::...
Zfish   196 GDIVKVTNGQHLPADMVIVSSSEPQAMCYTETSNLDGETNLKIRQGLSLTASFQSLEDLIALSGR 260

  Fly   401 FYVEKPQNDIHSFIATFCMAD------GSEDT---GLSVENTLWANTVVAAGTATGIVIYTGCET 456
            ...|.|...::.|..|..:.:      |.:..   |..:.||.|         ..|||:|||.::
Zfish   261 LECEGPNRHLYDFTGTLRLDNHNPAPLGPDQVLLRGAQLRNTQW---------VVGIVVYTGHDS 316

  Fly   457 RSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGGP-----------WY----- 505
            : :|.||   :|..|....:..:|.:....:.|:.|||.::...|..           ||
Zfish   317 K-LMQNS---TKAPLKRSNVERVTNMQILVLFGILLVMALVSSIGAAIWNKQHTDEACWYLSRAG 377

  Fly   506 ------RY-MFRFVLLFSYIIPISLRVNLDMGK----AFYSW--QMQNDSNIQGTVVRSTTIPEE 557
                  .| :..|::|::.:|||||.|.|::.|    .|.:|  :|.........:.|::.:.||
Zfish   378 DISLNFAYNLLTFIILYNNLIPISLLVTLEVVKFTQALFINWDVEMYYAETDTPAMARTSNLNEE 442

  Fly   558 LGRISYVLTDKTGTLTQNEMVFKKIHLGIVSH------DAD----TFHHIGQMIQKLSGNILQQQ 612
            ||::.|:.:|||||||.|.|.|||..:..:::      |.|    .|.|:.
Zfish   443 LGQVKYLFSDKTGTLTCNVMHFKKCTIAGITYGHFPDLDCDRSMEDFSHLP-------------- 493

  Fly   613 QGSLSSSSSGGDSTKPMMFGN-RMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTG 676
                |:|.:..:...|.:..| ....|...:..|.:..:|:||.|.|  :.|||:.:
Zfish   494 ----STSHNSTEFDDPALIQNIEKNHPTSPQICEFLTMMAVCHTVVP--EREDNQII-------- 544

  Fly   677 GNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDND 741
                                   |||:||||.||||..:.:|....||..:::.::.:...:.
Zfish   545 -----------------------YQASSPDEGALVKGAKSLGFVFTARTPHSVIIEARGKEQT-- 584

  Fly   742 ILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVV----MSSIVQYNDWLSEESGNMA 802
                |::|.:..|:|..|||.:||| :.||.:..|.||||.|    ::...||.:.........|
Zfish   585 ----YELLNVLEFSSNRKRMSVIVR-TPTGNLRLYCKGADNVIFERLNVTSQYKELTVAHLEQFA 644

  Fly   803 REGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQE 867
            .||||||..|...|.|..|.::...||.....:.||..|:....|.:|:.|.||..|.:|||||.
Zfish   645 TEGLRTLCFAYVDLEEGAYLEWLKEYNRISTVLKDRAQKLEECYELIEKNLLLLGATAIEDRLQA 709

  Fly   868 NVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHV-----LRSVKTRTDAHQEL- 926
            .|..|:..|..|.:::|:|||||.|||..|..|.:|:.....|.:     |.:.:....||...
Zfish   710 GVPETIATLMRADIKIWVLTGDKQETAINIGYSCRLVSHGMSLIIVNEDSLDATRATLTAHCSSL 774

  Fly   927 -NSFRRKQGHALVISGESLEVCLQY-YRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKR 989
             :|.|::...||:|.|::|:..|.: .|..||:||.:..||:|||.||.||:::|.:::||....
Zfish   775 GDSLRKENELALIIDGQTLKYALSFEVRQAFLDLALSCKAVICCRVSPLQKSEIVDMVKKHVKAI 839

  Fly   990 TCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQ 1054
            |.|:|||.|||.|||.|..||||.|.||.||:.:.|:||.|||::.||||:||..||.|......
Zfish   840 TLAIGDGANDVGMIQTAHVGVGISGNEGMQATNSSDYSIAQFSYLEKLLLVHGAWSYNRVTKCIL 904

  Fly  1055 FVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPE 1118
            :..::.:::..::..|:.|...|...|::.:.:..|:.::|..|.|:| :.|:..:.:..:.:|:
Zfish   905 YCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFDRPCSQQNMIRFPQ 969

  Fly  1119 LYKDLSKGRSLSYKTFFIWVLISIYQGGVI--MYGALILF------------------VDEFIHI 1163
            ||:........:.|.|  |       |..|  :..::|||                  || ::.:
Zfish   970 LYRITQNAEGFNTKVF--W-------GHCINALIHSIILFWFPLKALEHDTPFDNGNSVD-YLFV 1024

  Fly  1164 VAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYFDWEFI----------- 1217
            ..|.::.:::|..:...:....|.|...||...|:.|:::..||....  |..|
Zfish  1025 GNIVYTYVVVTVCLKAGMETTAWTRFSHLAVWGSMVLWMLFFAVYSAI--WPTIPIAPDMLGQAG 1087

  Fly  1218 -----WSYDFLWKVSLITLVSCL 1235
                 ||:   |...::...:||
Zfish  1088 RVMQCWSF---WLGLILVPTACL 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	PhoLip_ATPase_N	227..279	CDD:292826	21/51 (41%)
		ATPase-Plipid	228..1252	CDD:273734	314/1106 (28%)
		E1-E2_ATPase	323..525	CDD:278548	54/233 (23%)
		Cation_ATPase	<704..783	CDD:289987	28/78 (36%)
		HAD_like	<975..1019	CDD:304363	23/43 (53%)
		PhoLip_ATPase_C	1021..1249	CDD:292829	55/252 (22%)
atp8a2	XP_017209427.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578111
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.860