Protein Alignment CG31729 and atp8b1

DIOPT Version :10

• Sequence 1: NP_609634.1
• Gene: CG31729 / 34736
• FlyBaseID: FBgn0051729
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_001920510.4
• Gene: atp8b1 / 100148342
• ZFINID: ZDB-GENE-091116-14
• Length: 1249
• Species: Danio rerio
• Alignment Length: 1177
• Identity: 339/1177 - (28%)
• Similarity: 552/1177 - (46%)
• Gaps: 239/1177 - (20%)

  Fly   223 VNTEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFV 287
            :...::..|.|:..|||.:|||||.|:|||:...|||||.:.:.|.||.|.....||...||..|
Zfish    81 IKKSRYSGNAIKTYKYNVLTFLPLNLYEQFKRAANLYFLCLLVLQIIPQISTLPWYTTLVPLVLV 145

  Fly   288 LMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISG-YEMVPSSKLKVGDVIIVEKNERVPADL 351
            |.:|..::.||||.||:.|.|:|::|...|    ::| :.......|:||||:.:.||:.:|||:
Zfish   146 LGITAIKDLVDDLARHRMDKEINNRKCDVL----LNGRFVETRWMNLQVGDVVRLHKNDFIPADI 206

  Fly   352 ILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYT-QKLSRDSELHSIDASFYVEKPQNDIHSFIA 415
            :||.||:.:...:|.|.:|||||:.|.::.:..| ::|..:.:|...:|....|:|.|.:..|:.
Zfish   207 MLLSTSNPNSLCYVETAELDGETNLKFKMGLKVTDERLQEEQQLSQFNALVMCEEPNNRLDKFVG 271

  Fly   416 TFCMADGSEDTGLSVENTLWANTVVA-AGTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGL 479
            |  |...|:...|.::|.|.....|. .....|:||:.|.:|:.:.|..:.|.|...:|..:|.:
Zfish   272 T--MIWESQSYALDLDNMLLRGCKVRNTDICHGLVIFAGNDTKIMRNGGKTRFKRTRIDKLMNYM 334

  Fly   480 T------KVLFCAVLGL----------SLVMMMLKGFGGPWYRYMFR-------FVLLFSYIIPI 521
            .      .||.||.|.:          |....::.|..   |...:|       ::::.:.::||
Zfish   335 VYTIFVLLVLLCAGLAIGHTYWYESIGSKAWYLIDGLD---YTSSYRGFLSFWGYIIILNTMVPI 396

  Fly   522 SLRVNLD---MGKA-FYSWQMQ-----NDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEM 577
            ||.|:::   :|:: |.:|.:|     .|:..:.   |:||:.|:||:|.|:.:|||||||||.|
Zfish   397 SLYVSVEVIRLGQSKFINWDLQMYYADKDTPAKS---RTTTLNEQLGQIEYIFSDKTGTLTQNIM 458

  Fly   578 VFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWR 642
            .|||..:...::...|                       ::.....|..||:.|        .|.
Zfish   459 AFKKCTISGRTYGEPT-----------------------TADGVSLDRGKPVDF--------SWN 492

  Fly   643 EW-------------------------EAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPT 682
            ::                         |..:.|:|||.|. |.:.|.
Zfish   493 KYADRKFQFEDHFLISCIRSKKDPQVLEFFKLLSLCHTVM-VEEKEG------------------ 538

  Fly   683 KSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQ 747
                          |..||||||||.|||......|...::|..:|:|:|      :.|....|.
Zfish   539 --------------ELVYQAASPDEGALVTAARNFGFVFLSRTQDTITIQ------EMDKPQTYT 583

  Fly   748 ILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWLSEESGN----------MA 802
            :|.|..|.|:.|||.||:: ...|:|..|.||||.|:     |.. ||.:|.|          .|
Zfish   584 MLALLDFNSDRKRMSIILK-FPDGRIRLYCKGADTVI-----YQR-LSPQSKNKENTQEALDIFA 641

  Fly   803 REGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTESLERELELLCLTGVEDRLQE 867
            .|.||||.:..|.:::|::..:..::..|.:|:.||..::..|.|.:|::|.|:..|.:||:||:
Zfish   642 NETLRTLCLCYKDISQEEFDRWSRKHQTAAVSMVDRERELDEVYEEIEKDLLLIGATAIEDKLQD 706

  Fly   868 NVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHV-------LRSVKT--RTDAH 923
            .|..|:..|..|.:::|:|||||.|||..|..|.||:..:..:|.       ||:.:|  |||..
Zfish   707 GVPETIAKLAKADIKIWVLTGDKKETAENIGYSCQLLTDDMKIHYGEDVNVQLRNRQTQRRTDPQ 771

  Fly   924 ----QELNSFRRKQG-HALVISGESLEVCL----------------------------------- 948
                ::..||..:.| :||:|:|..|...|
Zfish   772 SRNKKQKESFFNEPGKNALIITGGWLNEILYEKKKKRRRLRLKKLRLRQNNQQSSSSTAPDSSQP 836

  Fly   949 ------QYYRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQAD 1007
                  :..:.:|:::|....||:|||.:|.|||.||:|::|:....|.::|||.|||:||:.||
Zfish   837 VDDWEKEKRQEDFVDMACECSAVICCRVTPKQKANVVSLVKKYKKAVTLSIGDGANDVNMIKTAD 901

  Fly  1008 AGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSA 1072
            .||||.|:||.||.::.|::..||..:.:|||:|||.||.|.....::..::....|.:...||.
Zfish   902 IGVGISGQEGMQAVMSSDYAFAQFCFLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWFSF 966

  Fly  1073 VFYLSSVALYQGFLMVGYSTLYTMFPVFSL-VLDQDITSETAVTYPELYKDLSKGRSLSYKTFFI 1136
            ....|:...|:.:.:..|:..|:..||..: :||||:..:.::.:|:||....:|...:|:.|||
Zfish   967 FNGFSAQTAYEDWFITLYNVCYSSLPVLLVGLLDQDVNDKLSLRFPKLYLPGQQGALFNYRNFFI 1031

  Fly  1137 WVLISIYQGGVIM---YGALILFV-------DEFIHIVAISFSALIMTELIMVALTVRTWHRLMV 1191
            .:...|:...:|.   |||.:..:       .::.....::.|:||:|..:.::|....|..:..
Zfish  1032 SLFHGIFTSLMIFFIPYGAFLQTMGQDGEAPSDYQSFAVVAASSLIITVNLQISLNTSYWTFVNF 1096

  Fly  1192 LAELFSLALYL-----ISLAVLHEYFDWEFIWS--------YDFLWKVSLITLVSC-LPLYIIKF 1242
            .|.|.|:|||.     |..|.:|..|...|.::        ..:||...::|:..| ||:..|:|
Zfish  1097 FAVLGSIALYFGIMFDIHSAGIHVIFPNTFTFTGAASNALRQPYLWLTIILTVGVCLLPVICIQF 1161

  Fly  1243 LRKKCSP 1249
            |.:...|
Zfish  1162 LYQTIYP 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31729	NP_609634.1	P-type_ATPase_APLT_Neo1-like	230..1177	CDD:319841	316/1082 (29%)
		Cation_ATPase	<704..781	CDD:463817	28/76 (37%)
atp8b1	XP_001920510.4	P-type_ATPase_APLT_Dnf-like	88..1047	CDD:319770	309/1047 (30%)