DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)k05911 and Klk12

DIOPT Version :10

Sequence 1:NP_723797.3 Gene:l(2)k05911 / 34731 FlyBaseID:FBgn0284244 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_081373.1 Gene:Klk12 / 69511 MGIID:1916761 Length:247 Species:Mus musculus


Alignment Length:252 Identity:85/252 - (33%)
Similarity:125/252 - (49%) Gaps:42/252 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   396 DQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHC----VAR-----MTSWDVA 451
            |:|:|..|:....:..||...||......|||.|:....:||||||    |.|     :|..|..
Mouse    18 DREKIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTAAHCRDKYVVRLGEHSLTKLDWT 82

  Fly   452 ALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTS 516
            ....|       |.|.:.|.|        ::| .:....:|:.:|.|:.|:..||.::|:.||:|
Mouse    83 EQLRH-------TTFSITHPS--------YQG-AYQNHEHDLRLLRLNRPIHLTRAVRPVALPSS 131

  Fly   517 PSQQSRSYSGQVATVAGWGSLREN-GPQPSILQKVDIPIWTNAECARKYGRAAPGGIIESMICA- 579
            ...     :|.:..|:|||:..:. .|.|..||.:::...:|..|...:    ||.:.|:|:|| 
Mouse   132 CVT-----TGAMCHVSGWGTTNKPWDPFPDRLQCLNLSTVSNETCRAVF----PGRVTENMLCAG 187

  Fly   580 GQAAKDSCSGDSGGPMVINDGGRYTQVGIVSWG-IG-CGKGQYPGVYTRVTSLLPWI 634
            |:|.||:|.||||||:|.  ||  ...|:|||| :| ||:...|||||:|.....||
Mouse   188 GEAGKDACQGDSGGPLVC--GG--VLQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWI 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)k05911NP_723797.3 CLIP 111..174 CDD:197829
PTZ00449 <198..>376 CDD:185628
Tryp_SPc 400..637 CDD:238113 83/248 (33%)
Klk12NP_081373.1 Tryp_SPc 21..240 CDD:214473 81/247 (33%)
Blue background indicates that the domain is not in the aligned region.

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