Protein Alignment l(2)k05911 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 97/310 - (31%)
• Similarity: 149/310 - (48%)
• Gaps: 56/310 - (18%)

  Fly   355 RPTY------PSYPSPVTTTTTTRRPVSGTSSEGLP-----------LQCGNKNPVTPDQERIVG 402
            :||:      |.....|...|...:.:...:|.| |           |.|| |:..||   |:||
Human   148 KPTFRAVEIGPDQDLDVVEITENSQELRMRNSSG-PCLSGSLVSLHCLACG-KSLKTP---RVVG 207

  Fly   403 GINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMT---SWDVAALTAHLGDYNIGT 464
            ...||...:||...:....:..||||::....:||||||..:.|   :|.|.|.:..||.:
Human   208 VEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSF---- 268

  Fly   465 DFEVQHVSRRIKRLVRHKGFEFSTLH---NDVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSG 526
                  .|..:.:::.   .||:.::   ||:|::.|..|:.|:..::|||||....:.:
Human   269 ------PSLAVAKIII---IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELT----- 319

  Fly   527 QVAT---VAGWGSLRENGPQPS-ILQKVDIPIWTNAECARKYGRAAPGGIIESMICAG--QAAKD 585
             .||   :.|||..::||.:.| ||.:..:.:..:..|  ....|..|.:.|.|:|||  :...|
Human   320 -PATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRC--NADDAYQGEVTEKMMCAGIPEGGVD 381

  Fly   586 SCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIY 635
            :|.||||||::. ...::..|||||||.|||....|||||:|::.|.|||
Human   382 TCQGDSGGPLMY-QSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIY 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628	5/26 (19%)
		Tryp_SPc	400..637	CDD:238113	82/248 (33%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	9/49 (18%)
		Tryp_SPc	204..429	CDD:214473	80/246 (33%)