Protein Alignment l(2)k05911 and habp2

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001103843.2
• Gene: habp2 / 553472
• ZFINID: ZDB-GENE-030131-4721
• Length: 546
• Species: Danio rerio
• Alignment Length: 598
• Identity: 142/598 - (23%)
• Similarity: 207/598 - (34%)
• Gaps: 206/598 - (34%)

  Fly   100 SGGW-----GPGEGSKCLTSRG-------QPGVCVRIDGCRQYYRLARQISIFTLRQWPQANGLG 152
            |||:     .|..|.||...:.       ..|.||||          ::...:..:.||...|..
Zfish    95 SGGFKCICPPPYIGKKCQNEKNVCKKVKCGNGDCVRI----------KKDPFYECKCWPPYRGSK 149

  Fly   153 L------------NGNMCNFFDMLGRVNNGICCTDIDANSFGVFPLPGTTTTTTTTTEMPSVVAD 205
            .            ||..|    :.||......||..:..| |.|...|:........|.......
Zfish   150 CKNAYACNPSPCQNGGTC----VKGRTRASFTCTCPEDYS-GRFCQVGSNDCYEGNGESYRGNVS 209

  Fly   206 EEDRE--------HVIPEGEVEGVYPPDVPRPEEPIDNANSVEDTPDFQDINTIEGNPPGADKKP 262
            |...|        ::||..|.||         .|.|...|...             ||.| |::|
Zfish   210 ETIEEIECLPWNHNLIPYKEFEG---------NESIGEHNYCR-------------NPDG-DREP 251

  Fly   263 EAEPVGEPVEQPISTQPASTIHPYQWPFGSFAGG-QWPPALPTHPPTTGGWPPPLPTHPPNHHYP 326
                                     |.|....|. ||                        ::..
Zfish   252 -------------------------WCFVKEKGKLQW------------------------NYCN 267

  Fly   327 THPTTGGVPSTKRTTPRPTSPARPTTTRRPTYPSYPSPVTTTTTTRRPVSGTSSEGLPLQCGNK- 390
            ..|.:            .|.|.:|.||  ||...:.                       .||..
Zfish   268 VKPCS------------ETEPEKPLTT--PTKLEFS-----------------------DCGKAA 295

  Fly   391 -NPVTPDQERIVGGINASPHEFPWIAVLFK-----SGKQF---CGGSLITNSHILTAAHCVARMT 446
             :.:.|   ||.||..:.|...||.| .|:     |...|   |||:||.:..|||||||:....
Zfish   296 FSMIAP---RIFGGRKSLPEAHPWQA-SFQVRPKGSNATFEHNCGGTLIDSCWILTAAHCIDEND 356

  Fly   447 SWDVAALTAHLGDYNIGTDF-EVQHVSRRIKRLVRHKGF--EFSTLHNDVAILTL--------SE 500
            .     :...||..|:..|. :.|.|  .:::::.|:.:  .|..|:||:|:|.|        :|
Zfish   357 E-----VRVELGGVNLEKDDPDKQFV--EVEKIIVHENYTETFDALYNDIALLKLKGRNGRCANE 414

  Fly   501 PVPFTREIQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARK-- 563
                :|.::..||||....:     |...|::|:|:..::....:.|....:.:.:.:.|..:
Zfish   415 ----SRSVRAACLPTDLFPE-----GTRCTISGYGATEKHHGVSTQLLDAKVLLISQSRCMSRNV 470

  Fly   564 YGRAAPGGIIESMICAG--QAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTR 626
            ||..    :.:||:|||  |...|||.||||||:|......:...|:||||..|||...||||.|
Zfish   471 YGNR----MDDSMMCAGYMQGKIDSCQGDSGGPLVCKKDNIHYIYGVVSWGDSCGKKNKPGVYAR 531

  Fly   627 VTSLLPWIYKNIK 639
            ||..:.||.:.::
Zfish   532 VTKFIDWINEKMR 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829	14/81 (17%)
		PTZ00449	<198..>376	CDD:185628	29/186 (16%)
		Tryp_SPc	400..637	CDD:238113	83/259 (32%)
habp2	NP_001103843.2	EGF_CA	80..112	CDD:238011	6/16 (38%)
		EGF_CA	158..190	CDD:238011	10/36 (28%)
		KR	195..273	CDD:214527	22/161 (14%)
		Tryp_SPc	303..542	CDD:238113	83/259 (32%)