Protein Alignment l(2)k05911 and ACR

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 88/278 - (31%)
• Similarity: 130/278 - (46%)
• Gaps: 43/278 - (15%)

  Fly   387 CG---NKNPVTPDQERIVGGINASPHEFPWIAVL----FKSGK-QFCGGSLITNSHILTAAHCVA 443
            ||   .:||  ....|||||..|....:||:..|    :.|.: ..|||||:.:..:||||||..
Human    29 CGLRFRQNP--QGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFV 91

  Fly   444 ---RMTSWDVAALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFT 505
               .:..|.:......: .|......:.....|.:::::.|:.:..:|..||:|::.::.|:...
Human    92 GKNNVHDWRLVFGAKEI-TYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCG 155

  Fly   506 REIQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQP-SILQK-----VDIPI-----WTNAE 559
            |.|.|.|||...:...|  ..|...|||||.:.|..|:| |||.:     :|:.:     |.|
Human   156 RFIGPGCLPHFKAGLPR--GSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYN-- 216

  Fly   560 CARKYGRAAPGGIIESMICAGQAAK--DSCSGDSGGPMVINDG--GRYTQVGIVSWGIGCGKGQY 620
                 ||..|     :.:|||....  |:|.||||||::..|.  ..|..|||.|||:||.:.:.
Human   217 -----GRVQP-----TNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKR 271

  Fly   621 PGVYTRVTSLLPWIYKNI 638
            ||:||.....|.||...|
Human   272 PGIYTATWPYLNWIASKI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628
		Tryp_SPc	400..637	CDD:238113	82/259 (32%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	81/257 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421