DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k05911 and CG11836

DIOPT Version :9

Sequence 1:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	103/262 - (39%)
Similarity:	162/262 - (61%)	Gaps:	13/262 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 TSSEGLPLQCGNKNPVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCV 442
            :|.:.....||..|    ::.|||||.....:::||:|.:...||..|||||:|..::|:|||||
  Fly    79 SSLKNCDCDCGFSN----EEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCV 139

  Fly   443 ARMTSWDVAALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTRE 507
            .::....:..:   .||::.....|.|.:.|.:..:::||.|:..|.:||:|:|.|.:|:.|::.
  Fly   140 KKLRKSKIRVI---FGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKI 201

  Fly   508 IQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGI 572
            |:|||||    :.:...:|::.||.|||...|.|..|||:.:|.:||.:..||..:  |.....|
  Fly   202 IKPICLP----RYNYDPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQ--RYKSTRI 260

  Fly   573 IESMICAGQAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKN 637
            ..||:|||:.:.|||.||||||:::::|.:|..|||||||:|||:..|||||:||:..:|||..|
  Fly   261 TSSMLCAGRPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSN 325

  Fly   638 IK 639
            ::
  Fly   326 LE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	96/234 (41%)
		Tryp_SPc	400..637	CDD:238113	97/236 (41%)
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	97/236 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3447
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	5	4.910