DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k05911 and ea

DIOPT Version :9

Sequence 1:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	104/333 - (31%)
Similarity:	157/333 - (47%)	Gaps:	66/333 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 STKRTTPRPTSPARPTTTRRPTYPSYPSPVTTTTTTRRPVSGTSSEGLPLQCGN--KNPVTPDQE 398
            |:..|||    |.:|..|.....|                       ||.||||  .|
  Fly    96 SSSETTP----PPKPNVTSNSLLP-----------------------LPGQCGNILSN------- 126

  Fly   399 RIVGGINASPHEFPWIAVL--FKS-GKQ--FCGGSLITNSHILTAAHCV---ARMTSWDVAALTA 455
            ||.||:.....||||:|::  .|| ||:  .||||||:..:::||:|||   |..|.|.::.:..
  Fly   127 RIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRL 191

  Fly   456 HLGDYNIGTDFEVQ----------HVSRRIKRLVRHKGFEFSTLH--NDVAILTLSEPVPFTREI 508
            ...|.|...|.||.          |:...::|.:.|..:..::.:  ||:|:|.|::.|.:|..:
  Fly   192 GEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFV 256

  Fly   509 QPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGII 573
            :|||||...:.:|.::.|....|||||. .|.....::..|..:..:...||...|  ::...::
  Fly   257 RPICLPLDVNLRSATFDGITMDVAGWGK-TEQLSASNLKLKAAVEGFRMDECQNVY--SSQDILL 318

  Fly   574 E-SMICA-GQAAKDSCSGDSGGPMVINDGGR----YTQVGIVSWG-IGCGKGQYPGVYTRVTSLL 631
            | :.:|| |:...|||.||||||::..|..:    |...|:||:| ..||...:|||||.|...:
  Fly   319 EDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYV 383

  Fly   632 PWIYKNIK 639
            .||...|:
  Fly   384 DWIQNTIE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	86/261 (33%)
		Tryp_SPc	400..637	CDD:238113	87/263 (33%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	86/261 (33%)
		Tryp_SPc	128..389	CDD:238113	87/263 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	3.010