Protein Alignment l(2)k05911 and KLK2

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 91/280 - (32%)
• Similarity: 130/280 - (46%)
• Gaps: 50/280 - (17%)

  Fly   380 SEGLPLQCGNKNPVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVAR 444
            |..|.:.|....|:.  |.|||||.....|..||...::..|...|||.|:....:||||||:.:
Human     7 SIALSVGCTGAVPLI--QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK 69

  Fly   445 MTS-WDVAALTAHLGDYNIGTDFEVQHVSRRI------------KRLVRHKGF---EFSTLHNDV 493
            .:. |        ||.:|:   ||.:...:|:            ..|::|:..   |.|:  :|:
Human    70 NSQVW--------LGRHNL---FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSS--HDL 121

  Fly   494 AILTLSEPVPFTREIQPICLPT-SPSQQSRSYSGQVATVAGWGSLR-ENGPQPSILQKVDIPIWT 556
            .:|.||||...|..::.:.||| .|:..:..|:      :||||:. |...:|..||.|.:.:.:
Human   122 MLLRLSEPAKITDVVKVLGLPTQEPALGTTCYA------SGWGSIEPEEFLRPRSLQCVSLHLLS 180

  Fly   557 NAECARKYGRAAPGGIIESMICAG--QAAKDSCSGDSGGPMVINDGGRYTQVGIVSWG-IGCGKG 618
            |..|||.|...    :.|.|:|||  ...||:|.||||||:|.|.    ...||.||| ..|...
Human   181 NDMCARAYSEK----VTEFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALP 237

  Fly   619 QYPGVYTRVTSLLPWIYKNI 638
            :.|.|||:|.....||...|
Human   238 EKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628
		Tryp_SPc	400..637	CDD:238113	84/257 (33%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	84/257 (33%)