Protein Alignment l(2)k05911 and F10

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 101/315 - (32%)
• Similarity: 150/315 - (47%)
• Gaps: 44/315 - (13%)

  Fly   356 PTYPSYPSPVTTTTTTRRPVS-GTSSEG--------------------LPLQCGNKNPVTPDQ-- 397
            ||.| ||....|....:|.|: .|||.|                    .|....:.|...|::
Human   166 PTGP-YPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGD 229

  Fly   398 ---ERIVGGINASPHEFPWIAVLF-KSGKQFCGGSLITNSHILTAAHCVARMTSWDVAALTAHLG 458
               .|||||......|.||.|:|. :..:.||||::::..:|||||||:.:...:.|     .:|
Human   230 NNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKV-----RVG 289

  Fly   459 DYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQQSRS 523
            |.|...: |.......::.:::|..|...|...|:|:|.|..|:.|...:.|.|||.....:|..
Human   290 DRNTEQE-EGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTL 353

  Fly   524 YSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGII-ESMICAGQAAK--D 585
            .:.:...|:|:|...|.|.|.:.|:.:::|......|     :.:...|| ::|.|||...|  |
Human   354 MTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC-----KLSSSFIITQNMFCAGYDTKQED 413

  Fly   586 SCSGDSGGPMVINDGGRYTQVGIVSWGIGCG-KGQYPGVYTRVTSLLPWIYKNIK 639
            :|.||||||.|......|...||||||.||. ||:| |:||:||:.|.||.:::|
Human   414 ACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKY-GIYTKVTAFLKWIDRSMK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628	7/19 (37%)
		Tryp_SPc	400..637	CDD:238113	84/241 (35%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203		5/19 (26%)
		Tryp_SPc	235..464	CDD:238113	84/240 (35%)
		O-glycosylated at one site	476..485