Protein Alignment l(2)k05911 and Tmprss13

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_006510195.1
• Gene: Tmprss13 / 214531
• MGIID: 2682935
• Length: 561
• Species: Mus musculus
• Alignment Length: 579
• Identity: 125/579 - (21%)
• Similarity: 187/579 - (32%)
• Gaps: 226/579 - (39%)

  Fly   254 NPPGADKKPEAEPV-GEPVEQPISTQPASTIHPYQWPFGSFAGGQWPPALPTH-PPTTGGWPPPL 316
            |...|...|:|.|. ..|...|....||.|      |         |.|.||. ||.......|.
Mouse     8 NSSPARTPPQASPARTSPARAPPQASPART------P---------PQASPTRTPPQASPARAPP 57

  Fly   317 PTHPPNHHYPTHPTTGGVPSTKRTTPRPTSPARPTTTRRPT-----------------YPSYPSP 364
            |...|....|...:....|.::.::.|.:|....:||..||                 .|:..:|
Mouse    58 PQASPARASPARASLARAPPSRSSSGRSSSARSASTTSSPTRVYLVRATPVGAVPIRASPARSAP 122

  Fly   365 VTTTT---------------TTRR----------------------------------------- 373
            .|..|               |.|:
Mouse   123 ATRATRESPGLSFPKFSWQETQRQLPLIGCVILLISLVISLILLYGGRETQSPRGTAVYFWRGHT 187

  Fly   374 -----------PV---------------------------------SGTSSEGLPL--------- 385
                       |:                                 ||:|.|.||:
Mouse   188 GIKYKEPLESCPIHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTD 252

  Fly   386 --------------------------------------------QCGNKNPVTPD---------Q 397
                                                        ||.::..|:..         .
Mouse   253 SKRTCQQLGFDSAYRTTEVAHRDITSSFLLSEYNTTIQESLYRSQCPSRRYVSLQCSHCGLRAMT 317

  Fly   398 ERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHC--VAR---MTSWDVAALTAHL 457
            .|||||...|..::||...|.......|||:||....:||||||  |.|   :..|.|.|.|::|
Mouse   318 GRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKLLEGWKVYAGTSNL 382

  Fly   458 GDYNIGTDFEVQH---VSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQ 519
                        |   .:..|.:::.:..:.......|:|::.||:|:..:..|.|.|||    .
Mouse   383 ------------HQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHIHPACLP----M 431

  Fly   520 QSRSYS-GQVATVAGWGSLRENGPQPS-ILQKVDIPIWTNAECARKYGRAAPGGIIESMICAG-- 580
            ..:::. .:...:.|:|..:|...:.| .|::|.:.:....:| ..| ......:...|:|||
Mouse   432 HGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKC-NDY-LVYDSYLTPRMMCAGDL 494

  Fly   581 QAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNIK 639
            :..:|||.||||||:|.....|:...|:.|||.|||:...|||||:||.:|||||:.::
Mouse   495 RGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWIYRKME 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628	35/240 (15%)
		Tryp_SPc	400..637	CDD:238113	80/248 (32%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065	29/128 (23%)
		SRCR_2	225..315	CDD:464747	9/89 (10%)
		Tryp_SPc	319..548	CDD:214473	78/246 (32%)