DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k05911 and CG12256

DIOPT Version :9

Sequence 1:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650166.2	Gene:	CG12256 / 14462452	FlyBaseID:	FBgn0038002	Length:	283	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	82/255 - (32%)
Similarity:	125/255 - (49%)	Gaps:	37/255 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 QERIVGGINASPHEF-PW---IAVLFKSGK--QFCGGSLITNSHILTAAHCVARMTSWDVAALTA 455
            |||:|||.:....|: |:   :..|.:|||  .|||||||..:.:|||||||....:..: ::.|
  Fly    44 QERVVGGYDVPEDEYVPYQVSMQFLTRSGKMRHFCGGSLIAPNRVLTAAHCVNGQNASRI-SVVA 107

  Fly   456 HLGDYNIGTDFEVQ----HVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPF-TREIQPICLPT 515
            .:.|.|..:.|..|    .::...:.||.          :|:|||.:..|... .:.:..|
  Fly   108 GIRDLNDSSGFRSQVQSYEMNENYQELVT----------SDIAILKIDPPFELDEKRVSTI---- 158

  Fly   516 SPSQQSRSYSGQVATVAGWGSLRE--NGP---QPSILQKVDIPIWTNAECARKYGRAAPGGIIES 575
            ..|......:.|...:.||||:..  .||   .|::|||:|....:|::|.....:     :.::
  Fly   159 DVSGSDMVGADQEVLLTGWGSVFHFGTGPFAKYPTVLQKLDYKTLSNSKCKETMTQ-----LTDT 218

  Fly   576 MICA-GQAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWI 634
            .||| .:..|.:|:||||||:|:..|..|.|||:||:|........|.|||||:....||
  Fly   219 EICALERFGKGACNGDSGGPLVMKSGESYKQVGVVSYGTAFCASNNPDVYTRVSMFDGWI 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	78/251 (31%)
		Tryp_SPc	400..637	CDD:238113	79/252 (31%)
CG12256	NP_650166.2	Tryp_SPc	46..278	CDD:214473	78/251 (31%)
CG12256	NP_650166.2	Tryp_SPc	47..280	CDD:238113	79/252 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010