Protein Alignment l(2)k05911 and PRSS21

DIOPT Version :10

• Sequence 1: NP_723797.3
• Gene: l(2)k05911 / 34731
• FlyBaseID: FBgn0284244
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 101/285 - (35%)
• Similarity: 144/285 - (50%)
• Gaps: 40/285 - (14%)

  Fly   372 RRPVSGTSSEGLPLQ--CGNKNPVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSH 434
            |:|   .|.|..||.  || :..:|   .|||||.:|....:||...|.......||.||:::..
Human    19 RKP---ESQEAAPLSGPCG-RRVIT---SRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRW 76

  Fly   435 ILTAAHC------VARMTSWDV--AALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHN 491
            .||||||      ::..:.|.|  ..||:....:::...:....|| .|....|:.|    ....
Human    77 ALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVS-NIYLSPRYLG----NSPY 136

  Fly   492 DVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSGQVAT---VAGWGSLRENG--PQPSILQKVD 551
            |:|::.||.||.:|:.||||||      |:.::..:..|   |.|||.::|:.  |.|..||:|.
Human   137 DIALVKLSAPVTYTKHIQPICL------QASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQ 195

  Fly   552 IPIWTNAECAR---KYGRAAPGGIIESMICAG--QAAKDSCSGDSGGPMVINDGGRYTQVGIVSW 611
            :.|..|:.|..   ||  :....|...|:|||  |..||:|.||||||:..|..|.:.|:|:|||
Human   196 VAIINNSMCNHLFLKY--SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSW 258

  Fly   612 GIGCGKGQYPGVYTRVTSLLPWIYK 636
            |:|||:...|||||.::....||.|
Human   259 GVGCGRPNRPGVYTNISHHFEWIQK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		PTZ00449	<198..>376	CDD:185628	2/3 (67%)
		Tryp_SPc	400..637	CDD:238113	91/255 (36%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	90/253 (36%)