DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mabi and Cebpb

DIOPT Version :9

Sequence 1:NP_609624.1 Gene:Mabi / 34727 FlyBaseID:FBgn0032493 Length:206 Species:Drosophila melanogaster
Sequence 2:NP_077039.3 Gene:Cebpb / 24253 RGDID:2327 Length:297 Species:Rattus norvegicus


Alignment Length:208 Identity:51/208 - (24%)
Similarity:75/208 - (36%) Gaps:49/208 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DMGRKIEKCDLQLKEELISRSG---TPCTSRSPFDAANQSVSLGFSDQDA----DFP------PL 64
            |.|.|..|.........:.|:|   .|.....|...|......||...|.    |.|      |.
  Rat    95 DYGAKPSKKPSDYGYVSLGRAGAKAAPPACFPPPPPAALKAEPGFEPADCKRADDAPAMAAGFPF 159

  Fly    65 PKRRRL-------GSSSSSVSYQSASPIITEAIQDIFKYHVNMVRK------------FPKKERS 110
            ..|..|       |||.|..:..|:||..|.:..|         .|            .|.|.::
  Rat   160 ALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPAD---------AKAAPAACFAGPPAAPAKAKA 215

  Fly   111 PKDQE--------RRNKNTIACRMSRRKKKFDDLQIEQQYKECSDEHLKIAEQSLRARVYLNHLK 167
            .|..:        ||.:|.||.|.||.|.|..:|:.:.:..|.:.|:.::.::..:....|:.|:
  Rat   216 KKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLR 280

  Fly   168 QLVKQEDHPLVSS 180
            .|.||...||::|
  Rat   281 NLFKQLPEPLLAS 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MabiNP_609624.1 None
CebpbNP_077039.3 Required for Lys-134 sumoylation. /evidence=ECO:0000250|UniProtKB:P17676 1..22
Required for MYC transcriptional repression. /evidence=ECO:0000250|UniProtKB:P28033 22..105 4/9 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 172..201 10/37 (27%)
bZIP_CEBPB 219..286 CDD:269860 17/66 (26%)
coiled coil 226..277 CDD:269860 13/50 (26%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 227..247 10/19 (53%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 249..256 1/6 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23334
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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